Mapping motor neuron activity to overt behavior in the leech
Mapping motor neuron activity to overt behavior in the leech
复制标题
将运动神经元活动映射到水蛭的明显行为
DOI：
--
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
W. Kristan
中科院分区：
文献类型：
--
作者：
R. J. Wilson;B. A. Skierczynski;J. Meyer;R. Skalak;W. Kristan
作为建立药用水蚤定量生物力学模型的第一步，我们测定了其体壁在生理尺寸范围内的被动特性。本研究的主要结果是：1.静息水蚤的椭圆形横截面是由紧张肌激活和体壁结构中固有的力(即残余应力)维持的。2.纵向和周向拉伸到最大生理尺寸所需的力在大小上相似。切掉几块体壁并不影响体壁远离切割边缘的被动纵向或周向特性。3.尽管肌肉横截面不同，但不同身体节段在相同的力作用下的应变(即尺寸变化的百分比)是相同的。4.5-羟色胺是一种已知的水蚤肌肉张力调节器，它影响所有生理肌肉长度的被动力。这表明纵肌至少对体壁的被动张力负责。5.我们提出了一个简单的体壁粘弹性模型。该模型捕捉了水蚤体壁对施加步长变化的被动反应的动力学。利用粘弹性模型预测的稳态被动张力，我们估计了在生理范围内将水蚤维持在任何给定长度所需的力。
As an initial step in constructing a quantitative biomechanical model of the medicinal leech (Hirudo medicinalis), we determined the passive properties of its body wall over the physiological range of dimensions. The major results of this study were:1.The ellipsoidal cross section of resting leeches is maintained by tonic muscle activation as well as forces inherent in the structure of the body wall (i.e., residual stress).2.The forces required for longitudinal and circumferential stretch to maximum physiological dimensions were similar in magnitude. Cutting out pieces of body wall did not affect the passive longitudinal or circumferential properties of body wall away from the edges of the cut.3.The strain (i.e., the percentage change in dimension) of different body segments when subject to the same force was identical, despite differences in muscle crosssections.4.Serotonin, a known modulator of tension in leech muscles, affected passive forces at all physiological muscle lengths. This suggests that the longitudinal muscle is responsible for at least part of the passive tension of the body wall.5.We propose a simple viscoelastic model of the body wall. This model captures the dynamics of the passive responses of the leech body wall to imposed step changes in length. Using steady-state passive tensions predicted by the viscoelastic model we estimate the forces required to maintain the leech at any given length over the physiological range.
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影响因子：
--
作者：
RODRIGUEZ, EK;OMENS, JH;MCCULLOCH, AD
通讯作者：
MCCULLOCH, AD
影响因子：
56.9
作者：
LUTZ, GJ;ROME, LC
通讯作者：
ROME, LC
影响因子：
56.9
作者：
ROME, LC;SWANK, D;CORDA, D
通讯作者：
CORDA, D
大鼠静脉和腔静脉的零应力状态。
DOI：
10.1115/1.2894083
发表时间：
1991
期刊：
Journal of biomechanical engineering
影响因子：
--
作者：
Xie,JP;Liu,SQ;Yang,RF;Fung,YC
通讯作者：
Fung,YC
药用水蛭缩短行为的多节协调分析和建模。
影响因子：
2.5
作者：
Wittenberg,G;KristanJr,WB
通讯作者：
KristanJr,WB