Effects of non-pharmacological pain treatments on brain states.
Effects of non-pharmacological pain treatments on brain states.
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DOI：
10.1016/j.clinph.2013.04.009
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发表时间：
2013-10
期刊：
影响因子：
--
通讯作者：
Hakimian S
中科院分区：
文献类型：
--
作者：
Jensen MP;Sherlin LH;Askew RL;Fregni F;Witkop G;Gianas A;Howe JD;Hakimian S
目的(1)相对于假的tDCS程序，评估一次四次非药物疼痛干预措施对疼痛和脑电(EEG)评估的脑振荡的影响，以及(2)确定与程序相关的疼痛强度变化与脑振荡变化的关联程度。30名有慢性疼痛的脊髓损伤患者在5种程序(催眠、冥想、经颅直流电刺激和神经反馈)和对照的假tDCS程序前后进行脑电检查和疼痛测量。每个程序都与大脑活动的不同变化模式有关，并且所有活动程序在至少三个带宽上都与对照组有显著差异。在EEG评估的大脑活动的变化和疼痛之间发现了非常微弱且大多不显著的关联。不同的非药物疼痛疗法对大脑振荡模式有不同的影响。然而，脑电评估的大脑振荡的变化与疼痛的变化没有明显的关联，因此这种变化似乎对解释这些治疗的好处没有帮助。这些结果提供了关于四种非药物治疗对疼痛和大脑活动的独特影响的新发现。
To (1) evaluate the effects of a single session of four non-pharmacological pain interventions, relative to a sham tDCS procedure, on pain and electroencephalogram- (EEG-) assessed brain oscillations, and (2) determine the extent to which procedure-related changes in pain intensity are associated with changes in brain oscillations. 30 individuals with spinal cord injury and chronic pain were given an EEG and administered measures of pain before and after five procedures (hypnosis, meditation, transcranial direct current stimulation [tDCS], and neurofeedback) and a control sham tDCS procedure. Each procedure was associated with a different pattern of changes in brain activity, and all active procedures were significantly different from the control procedure in at least three bandwidths. Very weak and mostly non-significant associations were found between changes in EEG-assessed brain activity and pain. Different non-pharmacological pain treatments have distinctive effects on brain oscillation patterns. However, changes in EEG-assessed brain oscillations are not significantly associated with changes in pain, and therefore such changes do not appear useful for explaining the benefits of these treatments. The results provide new findings regarding the unique effects of four non-pharmacological treatments on pain and brain activity.
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影响因子：
7.7
作者：
Brunoni, Andre Russowsky;Nitsche, Michael A.;Bolognini, Nadia;Bikson, Marom;Wagner, Tim;Merabet, Lotfi;Edwards, Dylan J.;Valero-Cabre, Antoni;Rotenberg, Alexander;Pascual-Leone, Alvaro;Ferrucci, Roberta;Priori, Alberto;Boggio, Paulo Sergio;Fregni, Felipe
通讯作者：
Fregni, Felipe
影响因子：
3
作者：
Dunn, BR;Hartigan, JA;Mikulas, WL
通讯作者：
Mikulas, WL
影响因子：
5.7
作者：
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通讯作者：
Oakley, DA
影响因子：
0.7
作者：
Carmody, James
通讯作者：
Carmody, James
影响因子：
2.2
作者：
CHEN, ACN;DWORKIN, SF;DRANGSHOLT, MT
通讯作者：
DRANGSHOLT, MT