Decision-making and motivation to participate in biomedical research in southwest Nigeria.
Decision-making and motivation to participate in biomedical research in southwest Nigeria.
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参与尼日利亚西南部生物医学研究的决策和动机。
DOI：
10.1111/j.1471-8847.2012.00326.x
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发表时间：
2012
影响因子：
2.2
通讯作者：
Kass,Nancy
中科院分区：
文献类型：
--
作者：
Osamor,PaulineE;Kass,Nancy
影响生物医学研究参与的动机和决策风格因研究类型、文化和国家而异。尽管有少量关于非西方文化中知情同意的文献，但很少有研究探讨参与者如何做出加入研究的决定。本研究旨在确定激励人们参与尼日利亚传统社区生物医学研究的因素，评估参与者让他人参与决策过程的程度，并研究研究决策的自主权问题。对尼日利亚城市社区的 100 名成年人（50 名男性，50 名女性）进行了一项描述性横断面研究，他们参加了一项生物医学研究。使用调查工具对受试者进行采访。三分之二的受访者表示参加生物医学研究是为了更多地了解自己的疾病，而 30% 的受访者希望获得一些医疗护理。超过四分之三 (78%) 的参与者与其他人讨论了入组决定，39% 的参与者表示获得了配偶或家庭成员的许可才能参与研究。女性表示在参与之前获得他人许可的可能性是男性的两倍多。更具体地说，一半的女性参与者表示在注册前曾寻求配偶的许可。研究结果表明，在这个社区中，知情同意被理解和实践为一种涉及其他人参与决策过程的关系活动。非西方国家需要对自主权、决策和参与研究的动机进行进一步的研究。
Motivations and decision‐making styles that influence participation in biomedical research vary across study types, cultures, and countries. While there is a small amount of literature on informed consent in non‐western cultures, few studies have examined how participants make the decision to join research. This study was designed to identify the factors motivating people to participate in biomedical research in a traditional Nigerian community, assess the degree to which participants involve others in the decision‐making process, and examine issues of autonomy in decision‐making for research. A descriptive cross‐sectional study was conducted with 100 adults (50 men, 50 women) in an urban Nigerian community who had participated in a biomedical research study. Subjects were interviewed using a survey instrument.Two‐thirds of the respondents reported participating in the biomedical study to learn more about their illness, while 30% hoped to get some medical care. Over three‐quarters (78%) of participants discussed the enrolment decision with someone else and 39% reported obtaining permission from a spouse or family member to participate in the study. Women were more than twice as likely as men to report obtaining permission from someone else before participating. More specifically, half of the female participants reported seeking permission from a spouse before enrolling. The findings suggest that informed consent in this community is understood and practised as a relational activity that involves others in the decision making process. Further studies are needed in non‐Western countries concerning autonomy, decision‐making, and motivation to participate in research studies.
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影响因子：
2.2
作者：
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通讯作者：
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DOI：
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期刊：
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DOI：
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发表时间：
2006
期刊：
IRB
影响因子：
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作者：
OnvomahaTindana,Paulina;Kass,Nancy;Akweongo,Patricia
通讯作者：
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