Utility of fluorodeoxyglucose positron emission tomography/computed tomography in patients with fever of unknown origin diagnosed as lymphoma.

Utility of fluorodeoxyglucose positron emission tomography/computed tomography in patients with fever of unknown origin diagnosed as lymphoma.
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DOI:
10.1159/000364812
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发表时间:
2014
期刊:
Medical principles and practice : international journal of the Kuwait University, Health Science Centre
影响因子:
--
通讯作者:
Sheng JF
Sheng JF
中科院分区:
其他
文献类型:
--
作者:
Sheng ZK;Ye J;Li JJ;Zhao K;Sheng JF

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目的评价氟-18氟脱氧葡萄糖正电子发射断层扫描(18F-FDG PET)/计算机断层扫描(CT)在不明原因发热(FUO)患者中的诊断价值,这些患者最终被诊断为淋巴瘤。回顾性研究于2009年3月至2012年3月在中国浙江大学医学院附属第一医院进行。分析连续FUO患者的PET/CT图像。在PET/CT扫描的1周内,如果临床需要,还进行了额外的组织学检查。共纳入73例连续患者。其中,34例(47%)的PET/CT结果提示存在淋巴瘤,29例(85%)诊断为确诊淋巴瘤; 39例(53%)的PET/CT结果显示不存在淋巴瘤,4例(10%)经活检诊断为淋巴瘤。最常见的淋巴瘤诊断是外周T细胞淋巴瘤(n = 16; 55 s %),其次是弥漫性大B细胞淋巴瘤(n = 9; 31 s %)。PET/CT诊断准确率为88%。在本研究中,PET/CT对淋巴瘤所致的FUO患者具有较高的诊断准确性,这表明PET/CT扫描对这类FUO患者是一种有价值的诊断工具。
To assess the efficacy of fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET)/computed tomography (CT) in the diagnosis of patients with fever of unknown origin (FUO), who were finally diagnosed as lymphoma. A retrospective study was performed in the First Affiliated Hospital, School of Medicine of Zhejiang University, China, from March 2009 to March 2012. The PET/CT images of consecutive patients with FUO were analyzed. Within 1 week of PET/CT scanning, additional histological tests were also performed if clinically needed. A total of 73 consecutive patients were included. Of these, 34 (47s%) had a PET/CT finding suggestive of the presence of lymphoma and 29 (85s%) had a diagnosis of confirmed lymphoma; 39 (53s%) had a PET/CT result revealing the absence of lymphoma and 4 (10s%) were diagnosed by biopsy as having lymphoma. The most frequent lymphoma diagnosis was peripheral T cell lymphoma (n = 16; 55s%), followed by diffuse large B cell lymphoma (n = 9; 31s%). The accuracy of PET/CT was 88s%. In this study, PET/CT had high diagnostic accuracy in patients with FUO resulting from lymphoma, which indicated that PET/CT scanning was a valuable diagnostic tool for these groups of patients with FUO.
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