Magnetic resonance imaging of the functional anatomy of the inferior rectus muscle in superior oblique muscle palsy.

Magnetic resonance imaging of the functional anatomy of the inferior rectus muscle in superior oblique muscle palsy.
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DOI:
10.1016/j.ophtha.2008.04.040
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发表时间:
2008-11
期刊:
影响因子:
13.7
通讯作者:
Demer JL
Demer JL
中科院分区:
医学1区
文献类型:
--
作者:
Jiang L;Demer JL

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生物力学模型一致表明,单靠上斜肌无力不足以解释上斜肌麻痹中常见的大斜视。磁共振成像(MRI)用于调查是否有任何大小或收缩性改变下直肌(IR)可能导致。前瞻性病例对照研究。单侧SO性麻痹17例,异性性麻痹18例。表面线圈用于在不同的凝视中获得连续的、2mm厚的高分辨率冠状MRI。IR和SO肌肉的横截面积在生产和生产中被确定,以评估大小和收缩性。SO性麻痹的诊断是基于临床表现,异常收缩力和SO大小小于正常的95%置信限。IR和SO肌肉的横截面积。患者中心性凝视斜视15.9±7.2(平均值±标准差)Δ,并表现为同病灶性SO萎缩和收缩力亚正常。平均同侧、对侧、正常红外截面积分别为28.5±3.5 mm2、31.9±3.8 mm2、31.8±5.8 mm2,平均收缩力分别为16.5±3.8 mm2、20.5±4.1 mm2、16.6±4.8 mm2。同侧病变的IR截面积和收缩力显著小于对侧病变(P < 0.01)。在SO麻痹中,对侧IR比同侧IR更大、更收缩,反映出可能是神经介导的变化,仅由于SO虚弱而增加了相对较小的斜视。SO性麻痹的功能亢进对侧IR衰退消退是一种生理治疗方法。
Biomechanical modeling consistently indicates that superior oblique (SO) weakness alone is insufficient to explain the large hypertropia often observed in SO palsy. Magnetic resonance imaging (MRI) was used to investigate if any size or contractility changes in the inferior rectus (IR) may contribute. Prospective, case control study. 17 patients with unilateral SO palsy, and 18 orthotropic subjects. Surface coils were used to obtain sets of contiguous, 2 mm thick high-resolution, coronal MRI in different gazes. Cross sectional areas of the IR and SO muscles were determined in supraduction and infraduction for evaluation of size and contractility. Diagnosis of SO palsy was based on clinical presentations, and subnormal contractility and SO size less than the normal 95% confidence limit. Cross sectional areas of the IR and SO muscles. Patients had 15.9 ± 7.2 (mean ± standard deviation) Δ central gaze hypertropia and exhibited ipsilesional SO atrophy and subnormal contractility. Mean ipsilesional, contralesional and normal IR cross-sections were 28.5 ± 3.5 mm2, 31.9 ± 3.8 mm2 and 31.8 ± 5.8 mm2, while mean contractility was 16.5 ± 3.8 mm2, 20.5 ± 4.1 mm2, and 16.6 ± 4.8 mm2, respectively. Ipsilesional IR cross-sections and contractility were significantly less than contralesional (P < 0.01). In SO palsy, the contralesional IR is larger and more contractile than the ipsilesional IR, reflecting likely neurally mediated changes that augment the relatively small hypertropia due to SO weakness alone. Recession of the hyperfunctioning contralesional IR recession in SO palsy is a physiologic therapy.
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发表时间: 2008-03-01
影响因子: 4.4
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