Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism.

Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism.
复制标题

DOI:
10.3390/md8030608
复制
发表时间:
2010-03-15
期刊:
影响因子:
5.4
通讯作者:
Dobson AD
Dobson AD
中科院分区:
医学2区
文献类型:
--
作者:
Kennedy J;Flemer B;Jackson SA;Lejon DP;Morrissey JP;O'Gara F;Dobson AD

文献摘要

参考文献

被引文献

相似文献

海洋环境极其多样,压力和温度变化巨大。然而,生命,特别是微生物生命,在整个海洋生物圈中蓬勃发展,微生物已经适应了所有不同的环境。大规模的DNA序列为基础的方法最近被用来调查海洋环境,这些研究表明,海洋港口前所未有的微生物多样性。新的基因家族的代表性,只有在这样的宏基因组数据集代表了海洋宏基因组的很大一部分。来自这些未经培养和高度多样化的微生物种群的如此多的新基因家族的存在,对理解和利用海洋环境的生物学和生物化学构成了挑战。新的宏基因组学和单细胞基因组学工具的应用为探索海洋生物群落的完整代谢多样性提供了新的途径。
The marine environment is extremely diverse, with huge variations in pressure and temperature. Nevertheless, life, especially microbial life, thrives throughout the marine biosphere and microbes have adapted to all the divergent environments present. Large scale DNA sequence based approaches have recently been used to investigate the marine environment and these studies have revealed that the oceans harbor unprecedented microbial diversity. Novel gene families with representatives only within such metagenomic datasets represent a large proportion of the ocean metagenome. The presence of so many new gene families from these uncultured and highly diverse microbial populations represents a challenge for the understanding of and exploitation of the biology and biochemistry of the ocean environment. The application of new metagenomic and single cell genomics tools offers new ways to explore the complete metabolic diversity of the marine biome.
DOI: 10.1126/science.280.5364.694
发表时间: 1998-05-01
期刊: SCIENCE
影响因子: 56.9
作者:
Azam, F
通讯作者: Azam, F
DOI: 10.1073/pnas.0503674102
发表时间: 2005-06-28
影响因子: 11.1
作者:
Beatty, JT;Overmann, J;Plumley, FG
通讯作者: Plumley, FG
DOI: 10.1074/jbc.m204517200
发表时间: 2002-09-20
影响因子: 4.8
作者:
Collins, T;Meuwis, MA;Gerday, C
通讯作者: Gerday, C
DOI: 10.1186/gb-2005-6-2-r14
发表时间: 2005
期刊: Genome biology
影响因子: 12.3
作者:
Dufresne A;Garczarek L;Partensky F
通讯作者: Partensky F
DOI: 10.1126/science.8303295
发表时间: 1994-02-11
期刊: SCIENCE
影响因子: 56.9
作者:
CHALFIE, M;TU, Y;PRASHER, DC
通讯作者: PRASHER, DC