The role of recently derived FT paralogs in sunflower domestication.
The role of recently derived FT paralogs in sunflower domestication.
复制标题
DOI：
10.1016/j.cub.2010.01.059
复制
发表时间：
2010-04-13
期刊：
影响因子：
--
通讯作者：
Rieseberg LH
中科院分区：
文献类型：
--
作者：
Blackman BK;Strasburg JL;Raduski AR;Michaels SD;Rieseberg LH
基因复制为表型多样化提供了重要的遗传原料来源，但很少有研究详细说明复制在物种内产生进化新奇的机制。在这里，我们调查了如何一组最近复制的同源花诱导FLOWESTLOCUS T（FT）的向日葵驯化作出了贡献。我们发现，这些重复表达的变化与野生和驯化向日葵开花行为的差异有关。此外，我们提出的遗传和功能的证据表明，移码突变的一个paranus，向日葵FT 1（HaFT 1），是一个主要的QTL开花时间，并经历了选择性的扫描在早期驯化。值得注意的是，这种显性负等位基因通过干扰另一种parabolic因子HaFT 4的作用来延迟开花。总之，这些数据表明，影响HaFT旁系同源物的表达，序列和基因相互作用的变化在向日葵驯化过程中发挥了关键作用。我们的研究结果还说明了新基因家族成员之间不断发展的相互作用在促进表型变化方面可能发挥的重要作用。
Gene duplication provides an important source of genetic raw material for phenotypic diversification, but few studies have detailed the mechanisms through which duplications produce evolutionary novelty within species. Here, we investigate how a set of recently duplicated homologs of the floral inducer FLOWERING LOCUS T (FT) has contributed to sunflower domestication. We find that changes in expression of these duplicates are associated with differences in flowering behavior between wild and domesticated sunflower. In addition, we present genetic and functional evidence demonstrating that a frameshift mutation in one paralog, Helianthus annuus FT 1 (HaFT1), underlies a major QTL for flowering time and experienced a selective sweep during early domestication. Notably, this dominant-negative allele delays flowering through interference with action of another paralog, HaFT4. Together, these data reveal that changes affecting the expression, sequence, and gene interactions of HaFT paralogs have played key roles during sunflower domestication. Our findings also illustrate the important role that evolving interactions between new gene family members may play in fostering phenotypic change.
登录
查看更多内容
影响因子：
11.6
作者：
Hayama, Ryosuke;Agashe, Bhavna;Coupland, George
通讯作者：
Coupland, George
影响因子：
11.6
作者：
Lin, Ming-Kuem;Belanger, Helene;Lucas, William J.
通讯作者：
Lucas, William J.
影响因子：
56.9
作者：
Kobayashi, Y;Kaya, H;Araki, T
通讯作者：
Araki, T
影响因子：
56.9
作者：
Böhlenius, H;Huang, T;Nilsson, O
通讯作者：
Nilsson, O
影响因子：
64.8
作者：
Hayama, R;Yokoi, S;Shimamoto, K
通讯作者：
Shimamoto, K