G-protein βγ subunits determine grain size through interaction with MADS-domain transcription factors in rice.
G-protein βγ subunits determine grain size through interaction with MADS-domain transcription factors in rice.
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G 蛋白 βγ 亚基通过与水稻 MADS 域转录因子的相互作用来决定颗粒大小
DOI:
10.1038/s41467-018-03047-9
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发表时间:
2018-02-27
影响因子:
16.6
通讯作者:
Fu X
中科院分区:
文献类型:
--
作者:
Liu Q;Han R;Wu K;Zhang J;Ye Y;Wang S;Chen J;Pan Y;Li Q;Xu X;Zhou J;Tao D;Wu Y;Fu X
The simultaneous improvement of grain quality and yield of cereal crops is a major challenge for modern agriculture. Here we show that a rice grain yield quantitative trait locusqLGY3encodes a MADS-domain transcription factor OsMADS1, which acts as a key downstream effector of G-protein βγ dimers. The presence of an alternatively spliced protein OsMADS1lgy3is shown to be associated with formation of long and slender grains, resulting in increases in both grain quality and yield potential of rice. The Gγ subunits GS3 and DEP1 interact directly with the conserved keratin-like domain of MADS transcription factors, function as cofactors to enhance OsMADS1 transcriptional activity and promote the co-operative transactivation of common target genes, thereby regulating grain size and shape. We also demonstrate that combiningOsMADS1lgy3allele with high-yield-associateddep1-1andgs3alleles represents an effective strategy for simultaneously improving both the productivity and end-use quality of rice.
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