Microstructures and properties of cancellous bone of avascular necrosis of femoral heads

Microstructures and properties of cancellous bone of avascular necrosis of femoral heads
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股骨头缺血性坏死松质骨的显微结构与性能

DOI:
10.1007/s10409-009-0309-8
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发表时间:
2010-02
影响因子:
3.5
通讯作者:
Yeh, Hsien Yang
Yeh, Hsien Yang
中科院分区:
工程技术2区
文献类型:
--
作者:
Dai, Ruchun;Wang, Peng;Yao, Xuefeng;Yeh, Hsien Yang

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本研究的目的是观察股骨头缺血性坏死(ANFH)松质骨的微观结构和特征。建立兔股骨头坏死模型。成功地研究了肿瘤的组织病理学特征。类固醇注射组(S.G.)对照组(C.G.)检查包括兔体重、血液学检查和三维结构。结果发现,当甘油三酯(TG)升高时,SD组血浆胆固醇(CHO)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)水平明显低于对照组,而脏器和组织的骨矿含量(BMC)和结构模型指数(SMI)显著降低。
The aim of this study is to investigate microscopic structure and characterize cancellous bone of avascular necrosis of the femoral head (ANFH). The rabbit model of the ANFH is established. The histopathologic features are studied successfully. The differences between the steroid-injection group (S.G.) and the controlled group (C.G.) are examined, including the weight of rabbits, the hematological examination and the three-dimensional structures. It is found that the plasma levels of cholesterol (CHO), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in S.G. are lower than those in C.G. when the triglyceride (TG) increased in the S.G.; but the bone mineral content (BMC) and the structural model index (SMI) of the organ and tissue decreased significantly in S.G. Three-dimensional structures of the femoral head are obtained using micro-computed tomography (CT) scanning and the mechanical model is established to analyze the influences of these structural changes on the mechanical properties of the cancellous bone.
DOI: 10.1088/0031-9155/52/1/005
发表时间: 2007-01
影响因子: 3.5
作者:
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期刊: Iyo denshi to seitai kogaku. Japanese journal of medical electronics and biological engineering
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