Retrivability in The Danish National Hospital Registry of HIV and hepatitis B and C coinfection diagnoses of patients managed in HIV centers 1995-2004.
Retrivability in The Danish National Hospital Registry of HIV and hepatitis B and C coinfection diagnoses of patients managed in HIV centers 1995-2004.
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DOI：
10.1186/1471-2288-8-25
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发表时间：
2008-04-25
影响因子：
4
通讯作者：
Hansen AB
中科院分区：
文献类型：
--
作者：
Obel N;Reinholdt H;Omland LH;Engsig F;Sørensen HT;Hansen AB
基于医院的出院登记越来越多地用于艾滋病毒的纵向流行病学研究。我们检查了丹麦国家医院登记处（DNHR）中HIV感染和慢性B型肝炎（HBV）和丙型肝炎（HCV）合并感染的登记完整性，该登记处覆盖了所有丹麦医院。丹麦艾滋病毒队列研究包括自1995年1月1日以来在丹麦艾滋病毒诊所接受治疗的所有艾滋病毒感染者。在1995年1月1日至2004年12月31日的10年期间，DHCS中诊断为HIV-1的所有2 033名丹麦患者都被纳入目前的分析。我们使用DHCS作为参考，以检查DNHR中记录的HIV和HBV和HCV合并感染的完整性。考克斯回归分析用于估计DNHR与DHCS相比的HIV诊断时间的风险比。在DHCS的2 033名艾滋病毒患者中，共有2 006人（99%）在DNHR登记感染艾滋病毒。其中，1，888人（93%）在首次艾滋病毒检测呈阳性后一年内在DNHR登记。CD 4 < 200个细胞/μl，病毒载量>= 100，000拷贝/ml，并且在2000年1月1日之后被诊断，与DNHR的早期登记相关，无论是在粗分析还是校正分析中。DHCS中登记的30例（23%）慢性HBV HIV患者（n = 129）和DHCS中登记的126例（48%）HCV HIV患者（n = 264）在DNHR中登记了这些诊断。DHCS未检出HBV感染者8例，DNHR检出HBV感染者17例，DHCS检出HCV感染者8例。因此，DHCS中登记HBV和HCV的阳性预测值估计为0.88和0.97，DNHR中为0.32和0.54。这项研究表明，来自国家医院数据库的二级数据对于识别诊断为艾滋病毒感染的患者可能是可靠的。然而，合并症数据的预测价值可能较低。
Hospital-based discharge registries are used increasingly for longitudinal epidemiological studies of HIV. We examined completeness of registration of HIV infections and of chronic hepatitis B (HBV) and hepatitis C (HCV) coinfections in the Danish National Hospital Registry (DNHR) covering all Danish hospitals. The Danish HIV Cohort Study (DHCS) encompasses all HIV-infected patients treated in Danish HIV clinics since 1 January 1995. All 2,033 Danish patients in DHCS diagnosed with HIV-1 during the 10-year period from 1 January 1995 to 31 December 2004 were included in the current analysis. We used the DHCS as a reference to examine the completeness of HIV and of HBV and HCV coinfections recorded in DNHR. Cox regression analysis was used to estimate hazard ratios of time to diagnosis of HIV in DNHR compared to DHCS. Of the 2,033 HIV patients in DHCS, a total of 2,006 (99%) were registered with HIV in DNHR. Of these, 1,888 (93%) were registered in DNHR within one year of their first positive HIV test. A CD4 < 200 cells/μl, a viral load >= 100,000 copies/ml and being diagnosed after 1 January 2000, were associated with earlier registration in DNHR, both in crude and adjusted analyses. Thirty (23%) HIV patients registered with chronic HBV (n = 129) in DHCS and 126 (48%) of HIV patients with HCV (n = 264) in DHCS were registered with these diagnoses in the DNHR. Further 17 and 8 patients were registered with HBV and HCV respectively in DNHR, but not in DHCS. The positive predictive values of being registered with HBV and HCV in DHCS were thereby estimated to 0.88 and 0.97 and in DNHR to 0.32 and 0.54. The study demonstrates that secondary data from national hospital databases may be reliable for identification of patients diagnosed with HIV infection. However, the predictive value of co-morbidity data may be low.
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影响因子：
7.2
作者：
Madsen, M;Davidsen, M;Osler, M
通讯作者：
Osler, M
影响因子：
158.5
作者：
Bozzette, SA;Ake, CF;Louis, TA
通讯作者：
Louis, TA
影响因子：
39.2
作者：
Lohse, Nicolai;Hansen, Ann-Brit Eg;Obel, Niels
通讯作者：
Obel, Niels
DOI：
10.3233/jrs-1995-7303
发表时间：
1995-01-01
期刊：
The International journal of risk & safety in medicine
影响因子：
--
作者：
Sorensen, H T;Hansen, I;Sabroe, S
通讯作者：
Sabroe, S
影响因子：
--
作者：
Lohse, N;Hansen, ABE;Obel, N
通讯作者：
Obel, N