Association Between Finger-to-Nose Kinematics and Upper Extremity Motor Function in Subacute Stroke: A Principal Component Analysis.
Association Between Finger-to-Nose Kinematics and Upper Extremity Motor Function in Subacute Stroke: A Principal Component Analysis.
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DOI：
10.3389/fbioe.2021.660015
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发表时间：
2021
影响因子：
5.7
通讯作者：
Huang XL
中科院分区：
文献类型：
--
作者：
Chen ZJ;He C;Xia N;Gu MH;Li YA;Xiong CH;Xu J;Huang XL
运动学分析有助于解释中风后运动恢复的程度和机制。本研究旨在探讨从主成分分析（PCA）中获得的指鼻测试的运动学成分及其与亚急性卒中幸存者上肢运动功能的关系。37名亚急性中风患者和20名健康成年人参加了这项研究。利用手指到鼻子任务（FNT）中的6个运动学指标进行主成分分析。脑卒中参与者的临床评估包括Fugl-Meyer上肢评估（FMA-UE）、动作研究臂测试（ARAT）和改良Barthel指数（MBI）。多变量回归模型包含三个主成分（PC），占91.3%方差。PC1以平均速度、峰值速度、运动单元数（NMU）和归一化综合加速度（NIJ）为主（48.8%）。PC2（31.1%）描述了达到峰值速度和移动时间的时间百分比。PC3（11.4%）达到峰值速度的剖面时间百分比。脑卒中个体FMA-UE的主成分回归方差（R2 = 0.71）高于ARAT （R2 = 0.59）和MBI （R2 = 0.29）。通过PCA鉴定的指鼻试验中的运动学成分与亚急性卒中的UE运动功能有关。PCA揭示了运动学指标之间的内在关联，这可能为UE评估和未来针对中风个体的运动学组件的干预增加价值。中国临床试验注册中心（http://www.chictr.org.cn/）于2019年10月17日发布，编号：ChiCTR1900026656。
Kinematic analysis facilitates interpreting the extent and mechanisms of motor restoration after stroke. This study was aimed to explore the kinematic components of finger-to-nose test obtained from principal component analysis (PCA) and the associations with upper extremity (UE) motor function in subacute stroke survivors. Thirty-seven individuals with subacute stroke and twenty healthy adults participated in the study. Six kinematic metrics during finger-to-nose task (FNT) were utilized to perform PCA. Clinical assessments for stroke participants included the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), and Modified Barthel Index (MBI). Three principal components (PC) accounting for 91.3% variance were included in multivariable regression models. PC1 (48.8%) was dominated by mean velocity, peak velocity, number of movement units (NMU) and normalized integrated jerk (NIJ). PC2 (31.1%) described percentage of time to peak velocity and movement time. PC3 (11.4%) profiled percentage of time to peak velocity. The variance explained by principal component regression in FMA-UE (R2 = 0.71) were higher than ARAT (R2 = 0.59) and MBI (R2 = 0.29) for stroke individuals. Kinematic components during finger-to-nose test identified by PCA are associated with UE motor function in subacute stroke. PCA reveals the intrinsic association among kinematic metrics, which may add value to UE assessment and future intervention targeted for kinematic components for stroke individuals. Chinese Clinical Trial Registry (http://www.chictr.org.cn/) on 17 October 2019, identifier: ChiCTR1900026656.
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影响因子：
3.7
作者：
Santisteban L;Térémetz M;Bleton JP;Baron JC;Maier MA;Lindberg PG
通讯作者：
Lindberg PG
DOI：
10.1016/j.jht.2012.06.005
发表时间：
2013-04
期刊：
Journal of hand therapy : official journal of the American Society of Hand Therapists
影响因子：
--
作者：
Lang CE;Bland MD;Bailey RR;Schaefer SY;Birkenmeier RL
通讯作者：
Birkenmeier RL
影响因子：
4.2
作者：
Alt Murphy, Margit;Willen, Carin;Sunnerhagen, Katharina S.
通讯作者：
Sunnerhagen, Katharina S.
影响因子：
4.2
作者：
Hsieh, Yu-Wei;Wang, Chun-Hou;Hsieh, Ching-Lin
通讯作者：
Hsieh, Ching-Lin
DOI：
10.1109/tnsre.2019.2928719
发表时间：
2019-08-01
影响因子：
4.9
作者：
Lin, Bor-Shing;Lee, I-Jung;Hwang, Yi-Ting
通讯作者：
Hwang, Yi-Ting