Effect of k-space-weighted image contrast and ultrasound focus size on the accuracy of proton resonance frequency thermometry.

Effect of k-space-weighted image contrast and ultrasound focus size on the accuracy of proton resonance frequency thermometry.
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DOI:
10.1002/mrm.27383
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发表时间:
2019-01
影响因子:
3.3
通讯作者:
Parker DL
Parker DL
中科院分区:
医学3区
文献类型:
--
作者:
Svedin BT;Dillon CR;Parker DL

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构建一个预测模型,描述当使用伪黄金角星状堆叠(SOS)采集时,k空间加权图像对比度(KWIC)窗口的持续时间和对称性如何影响不同大小超声病灶的时间分辨率。我们进行了质子共振频率(PRF)温度测量的调制分析,以创建不同的对称性和持续时间的KWIC窗口的时间调制传递函数(tMTF)。我们重建模拟超声加热轨迹和SOS k空间数据以及实验体模数据使用相同的轨迹。使用三种不同持续时间的对称和非对称KWIC窗口重建图像。模拟结果与tMTF预测,实验结果和原始模拟温度进行了比较。的tMTF表明,时间分辨率与KWIC重建取决于对象的大小。KWIC窗口持续时间影响SNR和欠采样伪影的严重性。准确度和响应延迟改善的KWIC窗口持续时间减少或KWIC平面内的加热区域的大小增加。随着窗口持续时间的减少,精度恶化。使用对称窗口消除了对加热区域尺寸的响应延迟,但引入了大的重建延迟。使用滑动KWIC窗口重构从SOS采集的PRF温度测量的准确度和精度取决于KWIC窗口的大小以及加热区域的大小和形状。任何物体尺寸的KWIC重建的tMTF都可以预测对所采集信号变化的时间响应-温度、对比度增强等。
To construct a predictive model that describes how the duration and symmetry of a k-space weighted image contrast (KWIC) window affects the temporal resolution of differently sized ultrasound foci when using a pseudo-golden angle stack-of-stars (SOS) acquisition. We performed a modulation analysis of proton resonance frequency (PRF) temperature measurements to create the temporal modulation transfer function (tMTF) for KWIC windows of different symmetry and temporal duration. We reconstructed simulated ultrasound heating trajectories and SOS k-space data as well as experimental phantom data using the same trajectories. Images were reconstructed using symmetric and asymmetric KWIC windows of three different temporal durations. Simulated results were compared against tMTF predictions, experimental results, and the original simulated temperatures. The tMTF shows that temporal resolution with KWIC reconstructions depend on the object size. KWIC window duration affected SNR and severity of undersampling artifacts. Accuracy and response delay improved as the KWIC window duration decreased or the size of the heated region within the KWIC plane increased. Precision worsened as the window duration decreased. Using a symmetric window eliminated the response delay to heated region size but introduced a large reconstruction delay. The accuracy and precision of PRF temperature measurements from a SOS acquisition using a sliding KWIC window reconstruction are dependent upon the size of the KWIC window and the size and shape of the heated region. The tMTF of KWIC reconstructions for any object size can predict the temporal response to changes in signal being acquired – temperature, contrast enhancement, etc.
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