Nanocrystals for the parenteral delivery of poorly water-soluble drugs.
Nanocrystals for the parenteral delivery of poorly water-soluble drugs.
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DOI:
10.1016/j.cossms.2012.10.004
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发表时间:
2012-12-01
影响因子:
11
通讯作者:
Yeo, Yoon
中科院分区:
文献类型:
--
作者:
Sun, Bo;Yeo, Yoon
Nanocrystals have drawn increasing interest in pharmaceutical industry because of the ability to improve dissolution of poorly water-soluble drugs. Nanocrystals can be produced by top-down and bottom-up technologies and have been explored for a variety of therapeutic applications. Here we review the methods of nanocrystal production and parenteral applications of nanocrystals. We also discuss remaining challenges in the development of nanocrystal products.
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