Developmental trajectories in children with and without autism spectrum disorders: the first 3 years.

Developmental trajectories in children with and without autism spectrum disorders: the first 3 years.
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患有自闭症谱系障碍和自闭症儿童的发育轨迹:头三年。

DOI:
10.1111/j.1467-8624.2012.01870.x
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发表时间:
2013-03
期刊:
影响因子:
4.6
通讯作者:
Faherty A
Faherty A
中科院分区:
心理学1区
文献类型:
--
作者:
Landa RJ;Gross AL;Stuart EA;Faherty A

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回顾性研究表明,自闭症谱系障碍(ASD)的发病主要分为两类:早期和晚期,经过一段相对健康的发展。这项前瞻性的纵向研究检查了235名6-36个月大的自闭症儿童的社会,语言和运动轨迹。儿童被分为:14个月时发现的ASD,14个月后发现的ASD,以及没有ASD。尽管在6个月时各组的初始发育水平相似,但ASD组此后表现出非典型的轨迹。早期ASD组从14个月到24个月的损害大于晚期ASD组,但在36个月时相当。无论ASD诊断的时间如何,一些ASD儿童都会出现发育高原和退化。研究结果表明ASD的临床前阶段持续时间不同。
Retrospective studies indicate 2 major classes of autism spectrum disorder (ASD) onset: early and later, after a period of relatively healthy development. This prospective, longitudinal study examined social, language, and motor trajectories in 235 children with and without a sibling with autism, ages 6–36 months. Children were grouped as: ASD identified by 14 months, ASD identified after 14 months, and no ASD. Despite groups’ initial similar developmental level at 6 months, ASD groups exhibited atypical trajectories thereafter. Impairment from 14 to 24 months was greater in the Early-ASD than the Later-ASD group, but comparable at 36 months. Developmental plateau and regression occurred in some children with ASD, regardless of timing of ASD diagnosis. Findings indicate a preclinical phase of varying duration for ASD.
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