Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis.

Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis.
复制标题

超声视网膜神经调节和声学视网膜假体。

DOI:
10.3390/mi11100929
复制
发表时间:
2020-10-13
期刊:
影响因子:
3.4
通讯作者:
Yue L
Yue L
中科院分区:
工程技术3区
文献类型:
--
作者:
Lo PA;Huang K;Zhou Q;Humayun MS;Yue L

文献摘要

参考文献

被引文献

相似文献

超声是一种新兴的非侵入性神经调节方法。过去的研究表明,超声波可以可逆地激活和抑制大脑中的神经活动。最近的研究表明,使用声频从0.5到43 MHz的超声波激活视网膜神经元是可能的,而不会对细胞造成可检测到的损害。该综述总结了探索视网膜对超声暴露的反应的初步研究,讨论了超声刺激的优点和局限性,并提供了发展声学视网膜假体的工程前景的概述。为了便于比较,本文还介绍了超声波刺激视皮层的研究。尽管如此,总结的研究仍处于早期阶段;超声视网膜刺激似乎是一项可行的技术,在非侵入性视力恢复方面显示出巨大的治疗潜力。
Ultrasound is an emerging method for non-invasive neuromodulation. Studies in the past have demonstrated that ultrasound can reversibly activate and inhibit neural activities in the brain. Recent research shows the possibility of using ultrasound ranging from 0.5 to 43 MHz in acoustic frequency to activate the retinal neurons without causing detectable damages to the cells. This review recapitulates pilot studies that explored retinal responses to the ultrasound exposure, discusses the advantages and limitations of the ultrasonic stimulation, and offers an overview of engineering perspectives in developing an acoustic retinal prosthesis. For comparison, this article also presents studies in the ultrasonic stimulation of the visual cortex. Despite that, the summarized research is still in an early stage; ultrasonic retinal stimulation appears to be a viable technology that exhibits enormous therapeutic potential for non-invasive vision restoration.
DOI: 10.1109/58.31798
发表时间: 1989-09-01
影响因子: 3.6
作者:
EBBINI, ES
通讯作者: EBBINI, ES
DOI: 10.1016/0301-5629(84)90216-3
发表时间: 1984-01-01
影响因子: 2.9
作者:
CHIVERS, RC;ROUND, WH;ZIENIUK, JK
通讯作者: ZIENIUK, JK
DOI: 10.1113/jphysiol.1971.sp009581
发表时间: 1971-01-01
影响因子: 5.5
作者:
CLELAND, BG;DUBIN, MW;LEVICK, WR
通讯作者: LEVICK, WR
DOI: 10.1016/j.cub.2013.10.029
发表时间: 2013-12-02
期刊: CURRENT BIOLOGY
影响因子: 9.2
作者:
Deffieux, Thomas;Younan, Youliana;Aubry, Jean-Francois
通讯作者: Aubry, Jean-Francois
DOI: 10.1126/science.1190897
发表时间: 2010-07-23
期刊: SCIENCE
影响因子: 56.9
作者:
Busskamp, Volker;Duebel, Jens;Roska, Botond
通讯作者: Roska, Botond