A Fast, Provably Accurate Approximation Algorithm for Sparse Principal Component Analysis Reveals Human Genetic Variation Across the World
A Fast, Provably Accurate Approximation Algorithm for Sparse Principal Component Analysis Reveals Human Genetic Variation Across the World
复制标题
稀疏主成分分析的快速、可证明准确的近似算法揭示了世界各地的人类遗传变异
DOI:
10.1007/978-3-031-04749-7_6
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Drineas, Petros
中科院分区:
文献类型:
--
作者:
Chowdhury, Agniva;Bose, Aritra;Zhou, Samson;Woodruff, David P.;Drineas, Petros
Principal component analysis (PCA) is a widely used dimensionality reduction technique in machine learning and multivariate statistics. To improve the interpretability of PCA, various approaches to obtain sparse principal direction loadings have been proposed, which are termed Sparse Principal Component Analysis (SPCA). In this paper, we presentThreSPCA, a provably accurate algorithm based on thresholding the Singular Value Decomposition for the SPCA problem, without imposing any restrictive assumptions on the input covariance matrix. Our thresholding algorithm is conceptually simple; much faster than current state-of-the-art; and performs well in practice. When applied to genotype data from the 1000 Genomes Project,ThreSPCAis faster than previous benchmarks, at least as accurate, and leads to a set of interpretable biomarkers, revealing genetic diversity across the world.
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影响因子:
3.3
作者:
J. K. Pritchard;Matthew Stephens;Peter Donnelly
通讯作者:
J. K. Pritchard;Matthew Stephens;Peter Donnelly
DOI:
10.1109/isit.2011.6034216
发表时间:
2011-06
期刊:
2011 IEEE International Symposium on Information Theory Proceedings
影响因子:
--
作者:
Megasthenis Asteris;Dimitris Papailiopoulos;G. N. Karystinos
通讯作者:
Megasthenis Asteris;Dimitris Papailiopoulos;G. N. Karystinos
DOI:
--
发表时间:
--
期刊:
--
影响因子:
--
作者:
Jun Z. Li;D. Absher;Hua Tang;Audrey M. Southwick;A. Casto;Sohini Ramachandran;H. Cann;G. Barsh
通讯作者:
Jun Z. Li;D. Absher;Hua Tang;Audrey M. Southwick;A. Casto;Sohini Ramachandran;H. Cann;G. Barsh
影响因子:
5.8
作者:
Bose, Aritra;Kalantzis, Vassilis;Drineas, Petros
通讯作者:
Drineas, Petros