The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update.

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update.
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DOI:
10.1093/nar/gkac247
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发表时间:
2022-07-05
影响因子:
14.9
通讯作者:
Briggs, Peter J.
Briggs, Peter J.
中科院分区:
生物学2区
文献类型:
--
作者:
Ostrovsky, Alexander E.;Mahmoud, Alexandru;Lonie, Andrew J.;Syme, Anna;Fouilloux, Anne;Bretaudeau, Anthony;Nekrutenko, Anton;Kumar, Anup;Eschenlauer, Arthur C.;DeSanto, Assunta D.;Guerler, Aysam;Serrano-Solano, Beatriz;Batut, Berenice;Gruening, Bjoern A.;Langhorst, Bradley W.;Carr, Bridget;Raubenolt, Bryan A.;Hyde, Cameron J.;Bromhead, Catherine J.;Barnett, Christopher B.;Royaux, Coline;Gallardo, Cristobal;Blankenberg, Daniel;Fornika, Daniel J.;Baker, Dannon;Bouvier, Dave;Clements, Dave;Morais, David A. de Lima;Tabernero, David Lopez;Lariviere, Delphine;Nasr, Engy;Afgan, Enis;Zambelli, Federico;Heyl, Florian;Psomopoulos, Fotis;Coppens, Frederik;Price, Gareth R.;Cuccuru, Gianmauro;Le Corguille, Gildas;Von Kuster, Greg;Akbulut, Gulsum Gudukbay;Rasche, Helena;Hans-Rudolf, Hotz;Eguinoa, Ignacio;Makunin, Igor;Ranawaka, Isuru J.;Taylor, James P.;Joshi, Jayadev;Hillman-Jackson, Jennifer;Goecks, Jeremy;Chilton, John M.;Kamali, Kaivan;Suderman, Keith;Poterlowicz, Krzysztof;Yvan, Le Bras;Lopez-Delisle, Lucille;Sargent, Luke;Bassetti, Madeline E.;Tangaro, Marco Antonio;van den Beek, Marius;Cech, Martin;Bernt, Matthias;Fahrner, Matthias;Tekman, Mehmet;Foell, Melanie C.;Schatz, Michael C.;Crusoe, Michael R.;Roncoroni, Miguel;Kucher, Natalie;Coraor, Nate;Stoler, Nicholas;Rhodes, Nick;Soranzo, Nicola;Pinter, Niko;Goonasekera, Nuwan A.;Moreno, Pablo A.;Videm, Pavankumar;Melanie, Petera;Mandreoli, Pietro;Jagtap, Pratik D.;Gu, Qiang;Weber, Ralf J. M.;Lazarus, Ross;Vorderman, Ruben H. P.;Hiltemann, Saskia;Golitsynskiy, Sergey;Garg, Shilpa;Bray, Simon A.;Gladman, Simon L.;Leo, Simone;Mehta, Subina P.;Griffin, Timothy J.;Jalili, Vahid;Yves, Vandenbrouck;Wen, Victor;Nagampalli, Vijay K.;Bacon, Wendi A.;de Koning, Willem;Maier, Wolfgang;Briggs, Peter J.

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Galaxy是一个成熟的、可通过浏览器访问的科学计算工作台。它使科学家能够共享,分析和可视化他们自己的数据,最大限度地减少技术障碍。在多个国家基础设施提供商的支持下,一个蓬勃发展的全球社区继续使用、维护和促进该项目,这些基础设施提供商能够提供免费的分析和培训服务。银河培训网络支持免费的,自我指导的,虚拟培训与>230集成教程。项目参与度指标在过去两年中持续增长,包括源代码贡献、出版物、包装为工具的软件包、注册用户及其日常分析工作,以及新的独立专业服务器。银河系统的主要技术发展包括:改进用户界面,用于启动包含许多文件的大规模分析;用于探索性数据分析的互动工具;以及一整套机器学习工具。Galaxy促成的重要科学发展包括脊椎动物基因组计划(VGP)组装工作流程和全球SARS-CoV-2合作。银河项目的代表是软件、管理服务、解决科学分析问题的软件应用程序和充满活力的全球社区的组合。反过来,每个领域的特点是新描绘的能力。
Galaxy is a mature, browser accessible workbench for scientific computing. It enables scientists to share, analyze and visualize their own data, with minimal technical impediments. A thriving global community continues to use, maintain and contribute to the project, with support from multiple national infrastructure providers that enable freely accessible analysis and training services. The Galaxy Training Network supports free, self-directed, virtual training with >230 integrated tutorials. Project engagement metrics have continued to grow over the last 2 years, including source code contributions, publications, software packages wrapped as tools, registered users and their daily analysis jobs, and new independent specialized servers. Key Galaxy technical developments include an improved user interface for launching large-scale analyses with many files, interactive tools for exploratory data analysis, and a complete suite of machine learning tools. Important scientific developments enabled by Galaxy include Vertebrate Genome Project (VGP) assembly workflows and global SARS-CoV-2 collaborations. The Galaxy Project is represented by a combination of software, managed services, application of the software for solving scientific analyses, and vibrant world-wide community. In turn, each area is characterized by new depicted capabilities.
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