A quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.
A quasi-analytic solution for real-time multi-exposure speckle imaging of tissue perfusion.
复制标题
用于组织灌注实时多曝光散斑成像的准分析解决方案。
DOI:
10.1101/2023.04.20.537736
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发表时间:
2023
期刊:
影响因子:
--
通讯作者:
Schaffer,ChrisB
中科院分区:
文献类型:
--
作者:
Rivera,DanielA;Schaffer,ChrisB
Laser speckle contrast imaging (LSCI) is a widefield imaging technique that enables high spatiotemporal resolution measurement of blood flow. Laser coherence, optical aberrations, and static scattering effects restrict LSCI to relative and qualitative measurements. Multi-exposure speckle imaging (MESI) is a quantitative extension of LSCI that accounts for these factors but has been limited to post-acquisition analysis due to long data processing times. Here we propose and test a real-time quasi-analytic solution to fitting MESI data, using both simulated and real-world data from a mouse model of photothrombotic stroke. This rapid estimation of multi-exposure imaging (REMI) enables processing of full-frame MESI images at up to 8 Hz with negligible errors relative to time-intensive least-squares methods. REMI opens the door to real-time, quantitative measures of perfusion change using simple optical systems.
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影响因子:
11.2
作者:
S. Albelda;S. Mette;D. Elder;R. Stewart;L. Damjanovich;M. Herlyn;C. Buck
通讯作者:
S. Albelda;S. Mette;D. Elder;R. Stewart;L. Damjanovich;M. Herlyn;C. Buck
影响因子:
9
作者:
G. Whalen;D. Ingber
通讯作者:
D. Ingber
影响因子:
11.2
作者:
Menter,DG;Steinert,BW;Sloane,BF;Gundlach,N;O'Gara,CY;Marnett,LJ;Diglio,C;Walz,D;Taylor,JD;Honn,KV
通讯作者:
Honn,KV
DOI:
10.1093/jnci/80.18.1461
发表时间:
1988-11
期刊:
Journal of the National Cancer Institute
影响因子:
--
作者:
K. Ugen;M. Mahalingam;P. Klein;K. Kao
通讯作者:
K. Ugen;M. Mahalingam;P. Klein;K. Kao
DOI:
10.1016/0167-4838(90)90229-9
发表时间:
1990
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Williams,J;Rucinski,B;Holt,J;Niewiarowski,S
通讯作者:
Niewiarowski,S