Metered reagent injection into microfluidic continuous flow sampling for conductimetric ocean dissolved inorganic carbon sensing
Metered reagent injection into microfluidic continuous flow sampling for conductimetric ocean dissolved inorganic carbon sensing
复制标题
将计量试剂注入微流体连续流动采样，用于电导海洋溶解无机碳传感
DOI：
10.1088/1361-6501/ab7405
复制
发表时间：
2020
影响因子：
2.4
通讯作者：
Tweedie M
中科院分区：
文献类型：
--
作者：
Tweedie M
海洋中总溶解无机碳(TCO2)的连续自主测量对于气候变化模型和海洋酸化测量是至关重要的。一种基于微流控电导率的方法将允许将微型化学分析系统集成到Argo海洋浮标中，以便以最小的试剂有效负载长期、高精度地分析溶解的二氧化碳。介绍了一种适用于样品酸化和CO2释放的精密计量方法。制作了激光刻蚀微流控蛇形流道限制器和非对称Y型流量计，流道尺寸可达∼75μm，用于调节海水和酸模拟物之间的计量比。对不同截面形状和面积的流动阻力与有限元模拟结果进行了比较。微流控计量电路由不同的电阻蛇形通道和Y结元件构成。采用300μm宽的蛇形通道，样品与酸的体积比(米比)高达100：1。在最高分辨率下，占地面积为600 mm 2。仅基于非对称Y型结的电路提供的最大计量比为16：1，占地面积为40 mm 2，∼精度为0.2%。在将计量装置集成到全TCO2分析微流控电路中时，需要进一步改进以确保这些小通道的完整性。
Continuous autonomous measurement of total dissolved inorganic carbon (TCO 2) in the oceans is critical for climate change modelling and ocean acidification measurement. A microfluidic conductivity-based approach will permit integration of miniaturised chemical analysis systems into Argo ocean floats, for long-term, high-accuracy depth profiling of dissolved CO 2 with minimal reagent payload. Precise metering, suitable for sample acidification and CO 2 liberation, is addressed. Laser etched microfluidic snake channel restrictors and asymmetric Y-meters were fabricated, with channel dimensions down to∼ 75 μm, to adjust metering ratios between seawater and acid simulants. Hydrodynamic resistances, from flow versus pressure measurements, were compared with finite element simulations for various cross-section profiles and areas. Microfluidic metering circuits were constructed from various resistance snake channels and Y-junction components. Sample to acid volume ratios (meter ratio) up to 100: 1 have been achieved with 300 μm wide snake channels for lengths> m. At highest resolution, the footprint would be> 600 mm 2. Circuits based solely on asymmetric Y-junctions gave maximum meter ratios of 16: 1 with a footprint of< 40 mm 2 and∼ 0.2% precision. Further refinement is required to ensure the integrity of such small channels in integration of metering units into full TCO 2 analysis microfluidic circuits.
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DOI：
10.1016/j.dsr.2009.04.006
发表时间：
2009-09-01
影响因子：
2.4
作者：
Sayles, F. L.;Eck, Calvert
通讯作者：
Eck, Calvert
影响因子：
6.1
作者：
G. Friederich;P. Brewer;R. Herlien;F. Chavez
通讯作者：
F. Chavez
ISO-CADICA：同位素连续、自动溶解无机碳分析仪。
DOI：
10.1002/rcm.6143
发表时间：
2012
期刊：
Rapid communications in mass spectrometry : RCM
影响因子：
--
作者：
A. Bass;M. Bird;N. Munksgaard;C. Wurster
通讯作者：
C. Wurster
海水中总溶解无机碳的高频分光光度测量。
影响因子：
11.4
作者：
Zhaohui Aleck Wang;Sophie N. Chu;Katherine A. Hoering
通讯作者：
Katherine A. Hoering
影响因子：
6.1
作者：
Legiret, Francois-Eric;Sieben, Vincent J.;Achterberg, Eric P.
通讯作者：
Achterberg, Eric P.