SARS-CoV-2 infection in UK university students: lessons from September-December 2020 and modelling insights for future student return.
SARS-CoV-2 infection in UK university students: lessons from September-December 2020 and modelling insights for future student return.
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DOI：
10.1098/rsos.210310
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发表时间：
2021-08
影响因子：
3.5
通讯作者：
Tildesley MJ
中科院分区：
文献类型：
--
作者：
Enright J;Hill EM;Stage HB;Bolton KJ;Nixon EJ;Fairbanks EL;Tang ML;Brooks-Pollock E;Dyson L;Budd CJ;Hoyle RB;Schewe L;Gog JR;Tildesley MJ
在本文中，我们使用多种方法来评估大学爆发程度，这些爆发可能导致社区溢出的程度以及控制措施的预期影响。首先，我们发现2020年末大学爆发的疫情分布与预期的到达学生感染的预期感染是一致的。考虑到一所大学的爆发，较大的居住堂构成了更高的传播风险。从大学爆发到更广泛社区的传播动态是复杂的，尽管有时确实会发生溢出，但有时甚至很大的爆发也不会向当地人口发出任何可检测的溢出信号。其次，我们探索了提出的控制措施，以重新开放和保持开放的大学。我们发现，在减少传播方面，使学生返回大学居住的归还的提议具有有限的价值。我们表明，学生遵守测试和自我隔离对于减少学期的传播可能更为重要。最后，我们探讨了在更可传播的变体的背景下测试学生的策略，发现为防止重大爆发是必要的频繁测试。
In this paper, we present work on SARS-CoV-2 transmission in UK higher education settings using multiple approaches to assess the extent of university outbreaks, how much those outbreaks may have led to spillover in the community, and the expected effects of control measures. Firstly, we found that the distribution of outbreaks in universities in late 2020 was consistent with the expected importation of infection from arriving students. Considering outbreaks at one university, larger halls of residence posed higher risks for transmission. The dynamics of transmission from university outbreaks to wider communities is complex, and while sometimes spillover does occur, occasionally even large outbreaks do not give any detectable signal of spillover to the local population. Secondly, we explored proposed control measures for reopening and keeping open universities. We found the proposal of staggering the return of students to university residence is of limited value in terms of reducing transmission. We show that student adherence to testing and self-isolation is likely to be much more important for reducing transmission during term time. Finally, we explored strategies for testing students in the context of a more transmissible variant and found that frequent testing would be necessary to prevent a major outbreak.
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影响因子：
9.3
作者：
Hellewell J;Russell TW;SAFER Investigators and Field Study Team;Crick COVID-19 Consortium;CMMID COVID-19 working group;Beale R;Kelly G;Houlihan C;Nastouli E;Kucharski AJ
通讯作者：
Kucharski AJ
SARS-COV-2血统的估计可传播和影响B.1.1.7在英国。
DOI：
10.1126/science.abg3055
发表时间：
2021-04-09
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Davies NG;Abbott S;Barnard RC;Jarvis CI;Kucharski AJ;Munday JD;Pearson CAB;Russell TW;Tully DC;Washburne AD;Wenseleers T;Gimma A;Waites W;Wong KLM;van Zandvoort K;Silverman JD;CMMID COVID-19 Working Group;COVID-19 Genomics UK (COG-UK) Consortium;Diaz-Ordaz K;Keogh R;Eggo RM;Funk S;Jit M;Atkins KE;Edmunds WJ
通讯作者：
Edmunds WJ
影响因子：
1.8
作者：
Harper, Paul R.;Moore, Joshua W.;Woolley, Thomas E.
通讯作者：
Woolley, Thomas E.
DOI：
10.1098/rspb.2013.1037
发表时间：
2013-08-22
期刊：
Proceedings. Biological sciences
影响因子：
--
作者：
Danon L;Read JM;House TA;Vernon MC;Keeling MJ
通讯作者：
Keeling MJ
DOI：
10.1016/j.ijid.2021.10.008
发表时间：
2021-12
期刊：
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
影响因子：
--
作者：
Hambridge HL;Kahn R;Onnela JP
通讯作者：
Onnela JP