Immediate and Sustained Effects of Interventions for Changing Physical Activity in People with Multiple Sclerosis: Meta-analysis of Randomized Controlled Trials.

Immediate and Sustained Effects of Interventions for Changing Physical Activity in People with Multiple Sclerosis: Meta-analysis of Randomized Controlled Trials.
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DOI:
10.1016/j.apmr.2020.03.017
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发表时间:
2020-08
影响因子:
4.3
通讯作者:
Motl, Robert W.
Motl, Robert W.
中科院分区:
医学1区
文献类型:
--
作者:
Kim, Yumi;Mehta, Tapan;Lai, Byron;Motl, Robert W.

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研究改变多发性硬化症(MS)患者体力活动行为的干预措施的直接和持续效果,并探讨可能调节干预对体力活动行为影响的因素(例如,干预类型和持续时间、体力活动测量类型、理论整合强度[研究设计中使用的理论程度]和研究质量)。 2017 年 10 月和 2018 年 10 月在 MEDLINE、CINAHL、PsychINFO 和 Google Scholar 等 4 个数据库中进行了系统检索。2019 年 9 月利用另外 2 个数据库(Embase 和 Scopus)和增强的检索词进行了更新检索。研究包括:(1) 纳入了一项随机对照试验设计的干预措施,旨在改变多发性硬化症成人的体力活动行为,即运动训练和行为干预(单独和联合); (2) 包括自我报告和/或设备测量的身体活动作为结果; (3) 包含干预前和干预后评估。提取即时(干预前至干预后)和持续(干预前至后续)身体活动结果和研究特征的数据。加权平均效应大小表示为标准化平均差(SMD)。使用统计之间的 Q 来比较每个分类调节器之间的异质性。身体活动结果的即时变化(n = 24)的平均 SMD 为 0.56,持续变化(n = 7)的平均 SMD 为 0.53。自我报告的身体活动测量产生的影响(SMD,0.64;n = 22)比设备测量的身体活动产生的影响更大(0.26;n = 7)。行为干预(SMD,0.71;n=9)似乎比运动训练(SMD,0.53;n=7)和综合干预(0.37;n=8)有更大的直接效果。目前的证据表明,干预措施对于增加并可能维持多发性硬化症成人的体力活动行为是有效的。效果似乎仅基于行为干预措施的实施而得到优化,并且这些干预措施可能能够支持长期的行为改变。
To examine the immediate and sustained effects of interventions for changing physical activity behavior in people with multiple sclerosis (MS), and to explore factors that might moderate intervention effects on physical activity behavior (eg, intervention type and duration, type of physical activity measurement, intensity of theory integration [degree of theory used in study design], and study quality). Systematic searches were conducted in 4 databases, including MEDLINE, CINAHL, PsychINFO, and Google Scholar, in October 2017 and October 2018. Updated searches were conducted in September 2019 with 2 additional databases (Embase and Scopus) and enhanced search terms. Studies were included that (1) incorporated a randomized controlled trial design of interventions that targeted change in physical activity behavior in adults with MS, namely, exercise training and behavioral intervention (alone and combined); (2) included self-reported and/or device-measured physical activity as an outcome; and (3) contained pre- and post-intervention assessments. Data were extracted for immediate (pre- to post-intervention) and sustained (pre-intervention to follow-up) physical activity outcomes and study characteristics. Weighted mean effect sizes were expressed as standardized mean differences (SMD). Heterogeneity between each categorical moderator was compared using Q between statistics. The mean SMD was 0.56 for immediate changes (n = 24) and 0.53 for sustained changes (n = 7) of physical activity outcomes. Self-reported physical activity measures yielded larger effects (SMD, 0.64; n = 22) than those of device-measured physical activity (0.26; n=7). There appeared to be larger immediate effects of behavioral interventions (SMD, 0.71; n=9) than exercise training (SMD, 0.53; n=7) and combined interventions (0.37; n=8). Current evidence demonstrates that interventions are efficacious for increasing and potentially sustaining physical activity behavior in adults with MS. The effects appear to be optimized based on the delivery of behavioral interventions alone, and these interventions may be capable of supporting long-term behavior change.
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