One source for distortion product otoacoustic emissions generated by low- and high-level primaries.

One source for distortion product otoacoustic emissions generated by low- and high-level primaries.
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低电平和高电平初级产生的失真产物耳声发射的来源之一。

DOI:
10.1121/1.1479151
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发表时间:
2002
期刊:
The Journal of the Acoustical Society of America
影响因子:
--
通讯作者:
I. Russell
I. Russell
中科院分区:
--
文献类型:
--
作者:
A. Lukashkin;V. Lukashkina;I. Russell

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畸变产物耳声发射(DPOAE)引起的低于60-70分贝声压级(SPL)的音调明显更敏感的耳蜗损伤。脆弱的,低级别的DPOAE已与假定的主动耳蜗过程,而相对强大的高级别的DPOAE组件已被归因于被动的,非线性的宏观力学特性的耳蜗。然而,有人提出,DPOAE对高和低SPL的脆弱性的差异是耳蜗对高和低SPL的响应方式的自然结果。主动过程增强基底膜(BM)振动,当主动过程受损时,基底膜振动减弱。然而,在高SPL的BM振动的主动过程的贡献是小的相比,占主导地位的被动力学性能的BM。因此,主动耳蜗放大的减少将在低SPL下对BM振动和DPOAE产生最大影响。为了区分“两个源”和“单源”的假设,我们分析了电平依赖性的缺口和相应的相位不连续性的DPOAE幅度和相位的函数的水平的小学绘图。在实验中,呋塞米被用来减少耳蜗放大,向上移动的缺口支持的结论,即低和高电平DPOAE是由一个单一的来源,即一个非线性放大器与饱和的I/O特性。
Distortion product otoacoustic emissions (DPOAE) elicited by tones below 60-70 dB sound pressure level (SPL) are significantly more sensitive to cochlear insults. The vulnerable, low-level DPOAE have been associated with the postulated active cochlear process, whereas the relatively robust high-level DPOAE component has been attributed to the passive, nonlinear macromechanical properties of the cochlea. However, it is proposed that the differences in the vulnerability of DPOAEs to high and low SPLs is a natural consequence of the way the cochlea responds to high and low SPLs. An active process boosts the basilar membrane (BM) vibrations, which are attenuated when the active process is impaired. However, at high SPLs the contribution of the active process to BM vibration is small compared with the dominating passive mechanical properties of the BM. Consequently, reduction of active cochlear amplification will have greatest effect on BM vibrations and DPOAEs at low SPLs. To distinguish between the "two sources" and the "single source" hypotheses we analyzed the level dependence of the notch and corresponding phase discontinuity in plots of DPOAE magnitude and phase as functions of the level of the primaries. In experiments where furosemide was used to reduce cochlear amplification, an upward shift of the notch supports the conclusion that both the low- and high-level DPOAEs are generated by a single source, namely a nonlinear amplifier with saturating I/O characteristic.
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