The Plant Target of Rapamycin: A Conduc TOR of Nutrition and Metabolism in Photosynthetic Organisms.
The Plant Target of Rapamycin: A Conduc TOR of Nutrition and Metabolism in Photosynthetic Organisms.
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DOI：
10.3390/genes11111285
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发表时间：
2020-10-29
期刊：
影响因子：
3.5
通讯作者：
Meyer C
中科院分区：
文献类型：
--
作者：
Ingargiola C;Turqueto Duarte G;Robaglia C;Leprince AS;Meyer C
生物体拥有许多感知营养的机制和有利的条件，这使得它们能够生长和发育。光合作用生物非常多样，从绿色的单细胞藻类到多细胞开花植物，但它们中的大多数都是固着的，因此无法逃脱它们所经历的生物和非生物压力。雷帕霉素的靶信号通路在所有真核生物中都是保守的，是生长和外在因素(如营养或胁迫)之间的中枢调节中心。然而，人们对这一途径在植物和藻类中的调节和作用知之甚少。尽管TOR途径的一些特征在整个进化过程中似乎是高度保守的，但其他特征在植物中明显不同，可能反映了对不同生活方式的适应，以及这个原始信号模块的重新布线以适应特定的要求。事实上，TOR参与了植物对一系列信号的反应，包括营养、激素、光、胁迫或病原体。本文综述了光合作用生物体中营养物质对TOR的调控，以及TOR在控制重要代谢途径中的作用，重点介绍了TOR与其他真核生物的异同。
Living organisms possess many mechanisms to sense nutrients and favorable conditions, which allow them to grow and develop. Photosynthetic organisms are very diverse, from green unicellular algae to multicellular flowering plants, but most of them are sessile and thus unable to escape from the biotic and abiotic stresses they experience. The Target of Rapamycin (TOR) signaling pathway is conserved in all eukaryotes and acts as a central regulatory hub between growth and extrinsic factors, such as nutrients or stress. However, relatively little is known about the regulations and roles of this pathway in plants and algae. Although some features of the TOR pathway seem to have been highly conserved throughout evolution, others clearly differ in plants, perhaps reflecting adaptations to different lifestyles and the rewiring of this primordial signaling module to adapt to specific requirements. Indeed, TOR is involved in plant responses to a vast array of signals including nutrients, hormones, light, stresses or pathogens. In this review, we will summarize recent studies that address the regulations of TOR by nutrients in photosynthetic organisms, and the roles of TOR in controlling important metabolic pathways, highlighting similarities and differences with the other eukaryotes.
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影响因子：
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发表时间：
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通讯作者：
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