Functional milestones and clinician ratings of everyday functioning in people with schizophrenia: overlap between milestones and specificity of ratings.
Functional milestones and clinician ratings of everyday functioning in people with schizophrenia: overlap between milestones and specificity of ratings.
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精神分裂症患者日常功能的功能里程碑和临床医生评级：里程碑和评级特异性之间的重叠。
DOI：
10.1016/j.jpsychires.2012.08.018
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发表时间：
2012-12
影响因子：
4.8
通讯作者：
Patterson TL
中科院分区：
文献类型：
--
作者：
Harvey PD;Sabbag S;Prestia D;Durand D;Twamley EW;Patterson TL
已知精神分裂症患者的日常功能在多个功能领域受到损害。然而，目前尚不清楚社会、职业和住宅领域的障碍如何相互重叠，此外，尽管有多种评定量表可用于评定日常功能，但也不清楚这些量表上的分数，特别是总分，与里程碑成就的关系。这一点很重要，因为通过药物或康复干预措施减少残疾的努力最终是根据其对日常功能的影响进行评估的，而这种影响往往与评定量表上的总分挂钩。在本文中，从VALERO研究，我们报告了195人与精神分裂症谁是一个综合的过程中，6个不同的功能状态评定量表。社会（已婚或同等学历），职业（曾就业，目前就业）和住宅（独立生活，经济责任）领域的里程碑成就进行了检查，他们相互重叠，并与评级量表上的评级。6个评定量表的总分与里程碑成就的相关性最低，里程碑成就彼此之间相当独立。从两个评级量表的分量表，特别是研究职业和住宅功能，具体涉及到里程碑的成就，在其功能领域，但不是其他里程碑。这些数据表明，日常功能测量的总体评分可能无法捕获功能里程碑，并强调功能里程碑具有多个决定因素，而不是这些评级量表试图捕获的能力变量。
Everyday functioning is known to be impaired in people with schizophrenia, across multiple functional domains. It is not clear, however, how impairments across social, vocational, and residential domains overlap with each other, Further, although there are multiple ratings scales available to rate everyday functioning, it is also not clear how scores on these scales, particularly total scores, relate to milestone achievement. This is important, because efforts to reduce disability with pharmacological or rehabilitative interventions are ultimately evaluated in terms of their impact on everyday functioning, which is often indexed with total scores on rating scales. In this paper from the VALERO study, we report on 195 people with schizophrenia who were rated with a comprehensive process on 6 different functional status rating scales. Milestone achievements in social (ever married or equivalent), vocational (ever employed, currently employed), and residential (living independently, financially responsible) domains were examined for their overlap with each other and with ratings on the rating scales. Total scores on the 6 rating scales were minimally related to milestone achievements and milestone achievements were quite independent of each other. Subscales from two of the rating scales, specifically examining vocational and residential functioning, were specifically related to milestone achievements in their functional domains, but not other milestones. These data suggest that global scores on everyday functioning measures may not capture functional milestones and highlight the fact that functional milestones have multiple determinants other then the ability variables that these rating scales attempt to capture.
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