Development of biomarkers to optimize pediatric patient management: what makes children different?
Development of biomarkers to optimize pediatric patient management: what makes children different?
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DOI:
10.2217/bmm.11.96
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发表时间:
2011-12
影响因子:
2.2
通讯作者:
Leeder JS
中科院分区:
文献类型:
--
作者:
Goldman J;Becker ML;Jones B;Clements M;Leeder JS
Despite the frequent utilization of biomarkers in medical practice, there is a relative paucity of information regarding validated pediatric biomarkers. Frequently, biomarkers found to be efficacious in adults are extrapolated to the pediatric clinical setting without considering that the pathogenesis of many diseases is distinctly different in children, and ontogeny directly influences disease evolution and therapeutic response in children. New and innovative approaches are necessary to provide reliable, validated biomarkers that can be used to improve and advance pediatric medical care.
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影响因子:
158.5
作者:
CZEIZEL, AE;DUDAS, I
通讯作者:
DUDAS, I
影响因子:
158.5
作者:
Bouzigon, Emmanuelle;Corda, Eve;Demenais, Florence
通讯作者:
Demenais, Florence
影响因子:
16.2
作者:
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通讯作者:
HEWETT, JE
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通讯作者:
International Kawasaki Disease Genetics Consortium
影响因子:
15.9
作者:
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通讯作者:
JOLIVET, J