A 20-channel receive-only mouse array coil for a 3 T clinical MRI system.

A 20-channel receive-only mouse array coil for a 3 T clinical MRI system.
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DOI:
10.1002/mrm.22791
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发表时间:
2011-08
影响因子:
3.3
通讯作者:
Heverhagen, Johannes T.
Heverhagen, Johannes T.
中科院分区:
医学3区
文献类型:
--
作者:
Keil, Boris;Wiggins, Graham C.;Triantafyllou, Christina;Wald, Lawrence L.;Meise, Florian M.;Schreiber, Laura M.;Klose, Klaus J.;Heverhagen, Johannes T.

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设计、建造了用于小鼠磁共振成像(MRI)的20通道相控阵线圈,并通过台架测量和高分辨率加速成像进行了验证。设计小型、高密度阵列的技术挑战已经被克服,使用以六角形重叠设计布置在圆柱体上的单个小直径线圈元件,以及相邻的低阻抗前置放大器,以进一步去耦合阵列元件。在体模和活体小鼠图像中模拟和定量评估了加速成像中的信噪比和噪声放大。20通道小鼠阵列与长度匹配的正交驱动的小动物鸟笼线圈的比较显示,模型外围和中心的信噪比分别提高了3倍和1.3倍。与较短但信噪比优化的鸟笼线圈(纵横比为1:1,只覆盖一半鼠标)相比,在体模边缘的信噪比提高了2倍,而在中心的信噪比相似。G因子测量表明,该线圈非常适合获取高速加速的图像。
A 20-channel phased-array coil for Magnetic Resonance Imaging (MRI) of mice has been designed, constructed and validated with bench measurements and high resolution accelerated imaging. The technical challenges of designing a small, high density array have been overcome using individual small-diameter coil elements arranged on a cylinder in a hexagonal overlapping design with adjacent low impedance preamplifiers to further decouple the array elements. Signal-to-noise ratio (SNR) and noise amplification in accelerated imaging were simulated and quantitatively evaluated in phantoms and in vivo mouse images. Comparison between the 20-channel mouse array and a length-matched quadrature driven small animal birdcage coil showed an SNR increase at the periphery and in the center of the phantom of 3-fold and 1.3-fold, respectively. Comparison to a shorter but SNR-optimized birdcage coil (aspect ratio 1:1 and only half mouse coverage) showed an SNR gain of 2-fold at the edge of the phantom and similar SNR in the center. G-factor measurements indicate that the coil is well suited to acquire highly accelerated images.
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