Pathogen-Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance.
Pathogen-Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance.
复制标题
DOI：
10.1038/npp.2016.194
复制
发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
Significant attention has been paid to the potential adaptive value of depression as it relates to interactions with people in the social world. However, in this review, we outline the rationale of why certain features of depression including its environmental and genetic risk factors, its association with the acute phase response and its age of onset and female preponderance appear to have evolved from human interactions with pathogens in the microbial world. Approaching the relationship between inflammation and depression from this evolutionary perspective yields a number of insights that may reveal important clues regarding the origin and epidemiology of the disorder as well as the persistence of its risk alleles in the modern human genome.
登录
查看更多内容
影响因子：
3.7
作者：
Annamanedi M;Kalle AM
通讯作者：
Kalle AM
DOI：
10.1152/ajpregu.00307.2007
发表时间：
2007-09-01
影响因子：
2.8
作者：
Bailey, Michael T.;Engler, Harald;Sheridan, John F.
通讯作者：
Sheridan, John F.
具有非典型特征的严重抑郁症的流行病学：来自国家酒精和相关疾病的国家流行病学调查的结果（NESARC）。
DOI：
10.4088/jcp.10m06227
发表时间：
2012-02
期刊：
The Journal of clinical psychiatry
影响因子：
--
作者：
Blanco C;Vesga-López O;Stewart JW;Liu SM;Grant BF;Hasin DS
通讯作者：
Hasin DS
影响因子：
2.9
作者：
AUBERT, A;GOODALL, G;DANTZER, R
通讯作者：
DANTZER, R
影响因子：
15.1
作者：
Avitsur, R;Kavelaars, A;Sheridan, JF
通讯作者：
Sheridan, JF