Cardiac Size, Shape, and Ventricular Contractility in Fetuses at Sea Level With an Estimated Weight Less-than 10th Centile.
Cardiac Size, Shape, and Ventricular Contractility in Fetuses at Sea Level With an Estimated Weight Less-than 10th Centile.
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DOI：
10.1002/jum.15954
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发表时间：
2022-11
影响因子：
2.3
通讯作者：
DeVore, Greggory R.
中科院分区：
文献类型：
--
作者：
Lee, Wesley;Mack, Lauren M.;Miremadi, Roxanna;Furtun, Betul Yilmaz;Sangi-Haghpeykar, Haleh;DeVore, Greggory R.
旨在研究估计胎儿体重 (EFW) < 海平面第十百分位数（休斯顿）的胎儿的心脏大小、形状和心室收缩力。一项前瞻性超声研究检查了 37 名在海平面 EFW < 10th centile 的胎儿。使用高频电影剪辑来评估 4 腔视图，包括舒张末期测量和整体球形指数。用斑点追踪方法分析两个心室的大小、形状和收缩性。 Z 分数使用正常对照的平均值±标准差 (SD) 计算。如果 Z 得分值 <−1.65 或 >+1.65，则测量结果异常。将参数异常的小胎儿的比例与正常参考范围进行比较。结果与丹佛高海拔地区小胎儿的类似已发表研究进行了比较。大约三分之一 EFW < 10th 百分位的休斯顿胎儿具有增大的球状四腔心脏，右心室 (RV) 面积、RV 基部 - 心尖长度、RV 基部宽度和左心室 (LV) 基部 - 心尖长度测量值增加。常出现双侧心室肥厚。休斯顿胎儿心室收缩力增强的比例增加。然而，海拔较高的胎儿心室收缩力下降更为普遍。海平面妊娠晚期的胎儿，EFW < 10th centile，通常与增大的球状心脏有关。与对照组相比，他们的整体和纵向心室收缩力有所增加。高海拔地区的胎儿心脏也呈增大的球状，但与海平面地区的胎儿相比，心室收缩力下降的病例比例更高。
To investigate cardiac size, shape, and ventricular contractility in fetuses with estimated fetal weight (EFW) <10th centile at sea level (Houston). A prospective ultrasound study examined 37 fetuses with EFW <10th centile at sea level. High-frequency cine clips were used to evaluate the 4-chamber view including end-diastolic measurements and global sphericity index. The size, shape, and contractility of both ventricles were analyzed with speckle tracking methods. Z scores were calculated using the mean ± standard deviation (SD) derived from normal controls. Measurements were abnormal if their Z score values were <−1.65 or >+1.65. The proportion of small fetuses with abnormal parameters was compared to normal reference ranges. Results were compared to a similar published study of small fetuses at higher altitude in Denver. About one-third of Houston fetuses with EFW <10th centile had enlarged globular shaped 4-chamber hearts with increased right ventricle (RV) area, RV basal-apical length, RV base width, and left ventricle (LV) basal-apical length measurements. Bilateral ventricular hypertrophy was often present. An increased proportion of Houston fetuses had increased ventricular contractility. However, decreased ventricular contractility was more prevalent for higher altitude fetuses. Third trimester fetuses at sea level, with an EFW <10th centile, were often associated with enlarged and globular-shaped hearts. They had increased global and longitudinal ventricular contractility as compared to controls. Higher altitude fetuses also had enlarged globular-shaped hearts but with a greater proportion of cases having decreased ventricular contractility as compared to the sea level cohort.
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影响因子：
9.8
作者：
Crispi, Fatima;Figueras, Francesc;Gratacos, Eduard
通讯作者：
Gratacos, Eduard
影响因子：
37.8
作者：
Crispi, Fatima;Bijnens, Bart;Gratacos, Eduard
通讯作者：
Gratacos, Eduard
影响因子：
7.1
作者：
DeVore, G. R.;Haxel, C.;Cuneo, B. F.
通讯作者：
Cuneo, B. F.
影响因子：
3
作者：
DeVore, Greggory R.;Klas, Berthold;Sklansky, Mark
通讯作者：
Sklansky, Mark
影响因子：
2.3
作者：
DeVore, Greggory R.;Satou, Gary;Sklansky, Mark
通讯作者：
Sklansky, Mark