Arsenic binding to proteins.
Arsenic binding to proteins.
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DOI:
10.1021/cr300015c
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发表时间:
2013-10-09
期刊:
影响因子:
62.1
通讯作者:
Le, X. Chris
中科院分区:
文献类型:
--
作者:
Shen, Shengwen;Li, Xing-Fang;Cullen, William R.;Weinfeld, Michael;Le, X. Chris
Arsenic is a trace element found in the earth, s crust at an average concentration of∼ 5 μg/g (ppm). Although its relative abundance in the earth, s crust is about 54th, arsenic can become concentrated in some parts of the world because of natural mineralization. Arsenic is a component of 245 minerals, associated most frequently with other metals such as copper, gold, lead, and zinc in sulfidic ores. 1− 3 When disturbed by natural processes, such as weathering, biological activity, and volcanic eruption, arsenic may be released into the environment. Anthropogenic activities, such as combustion of fossil fuels, mining, ore smelting, and well drilling, also mobilize and introduce arsenic into the environment. Chronic exposure to arsenic from groundwater has been recognized to cause the largest environmental health disaster in the world, putting more than 100 million people at risk of cancer and other arsenic-related diseases. 4, 5 Because of its
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