Positive imagery cognitive bias modification (CBM) and internet-based cognitive behavioral therapy (iCBT): a randomized controlled trial.
Positive imagery cognitive bias modification (CBM) and internet-based cognitive behavioral therapy (iCBT): a randomized controlled trial.
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DOI：
10.1016/j.jad.2015.02.026
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发表时间：
2015-06-01
影响因子：
6.6
通讯作者：
Andrews G
中科院分区：
文献类型：
--
作者：
Williams AD;O'Moore K;Blackwell SE;Smith J;Holmes EA;Andrews G
越来越多的证据表明，基于积极形象的认知偏差修正（CBM）可能有潜力作为抑郁症状的独立靶向干预或作为现有治疗的辅助手段。我们试图确定这种形式的CBM在互联网认知行为疗法（iCBT）治疗抑郁症之前提供的益处。一项随机对照试验（RCT），对符合重度抑郁症诊断标准的参与者（N=75，69%女性，平均年龄=42）进行为期1周的互联网提供的积极CBM与积极对照条件;随后对两组进行为期10周的iCBT计划。改良的意向治疗边际和混合效应模型表明，CBM干预或iCBT计划后的条件之间没有显着差异。在这两种情况下，抑郁和解释偏倚（PHQ 9、BDI-II、AST-D）的主要测量值均显著降低（Cohen标准差0.57 -1.58，95% CI= 0.12 -2.07）。对于痛苦、残疾、焦虑和重复性消极思维的次要指标（K10、WHODAS、STAI、RTQ），观察到较大的效应量降低（Cohen s d. 81 - 1. 32，95% CI=. 31 - 1. 79）。对完成所有7次CBM的参与者样本进行的符合方案分析表明，在CBM（Hedges g. 55-. 88，95% CI=-. 03 - 1. 46）和iCBT（PHQ 9，K10）后，阳性组在抑郁症状（PHQ 9，BDI-II）和心理困扰（K10）方面优于对照组。大多数（>70%）在3个月随访时不再符合抑郁症的诊断标准。控制条件包含许多活性成分，因此可能代表了较小的“剂量”的积极条件。结果提供了初步的支持，成功整合基于图像的CBM到现有的基于互联网的抑郁症治疗。
Accruing evidence suggests that positive imagery-based cognitive bias modification (CBM) could have potential as a standalone targeted intervention for depressive symptoms or as an adjunct to existing treatments. We sought to establish the benefit of this form of CBM when delivered prior to Internet cognitive behavioral therapy (iCBT) for depression A randomized controlled trial (RCT) of a 1-week Internet-delivered positive CBM vs. an active control condition for participants (N=75, 69% female, mean age=42) meeting diagnostic criteria for major depression; followed by a 10-week iCBT program for both groups. Modified intent-to-treat marginal and mixed effect models demonstrated no significant difference between conditions following the CBM intervention or the iCBT program. In both conditions there were significant reductions (Cohen׳s d .57–1.58, 95% CI=.12–2.07) in primary measures of depression and interpretation bias (PHQ9, BDI-II, AST-D). Large effect size reductions (Cohen׳s d .81–1.32, 95% CI=.31–1.79) were observed for secondary measures of distress, disability, anxiety and repetitive negative thinking (K10, WHODAS, STAI, RTQ). Per protocol analyses conducted in the sample of participants who completed all seven sessions of CBM indicated between-group superiority of the positive over control group on depression symptoms (PHQ9, BDI-II) and psychological distress (K10) following CBM (Hedges g .55–.88, 95% CI=−.03–1.46) and following iCBT (PHQ9, K10). The majority (>70%) no longer met diagnostic criteria for depression at 3-month follow-up. The control condition contained many active components and therefore may have represented a smaller ‘dose’ of the positive condition. Results provide preliminary support for the successful integration of imagery-based CBM into an existing Internet-based treatment for depression.
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影响因子：
10.3
作者：
Morina, Nexhmedin;Deeprose, Catherine;Pusowski, Christina;Schmid, Marina;Holmes, Emily A.
通讯作者：
Holmes, Emily A.
影响因子：
2.4
作者：
Blackwell, Simon E.;Holmes, Emily A.
通讯作者：
Holmes, Emily A.
影响因子：
5.9
作者：
JACOBSON, NS;TRUAX, P
通讯作者：
TRUAX, P
影响因子：
4.6
作者：
Mathews, A;Mackintosh, B
通讯作者：
Mackintosh, B
DOI：
10.1080/00048670902873722
发表时间：
2009-01-01
影响因子：
4.6
作者：
Perini, Sarah;Titov, Nickolai;Andrews, Gavin
通讯作者：
Andrews, Gavin