Reliability of the relationship between hippocampal unit activity and sensory-behavioral events in the rat.
Reliability of the relationship between hippocampal unit activity and sensory-behavioral events in the rat.
复制标题
大鼠海马单位活动与感觉行为事件之间关系的可靠性。
DOI：
10.1016/0014-4886(82)90032-2
复制
发表时间：
1982
影响因子：
5.3
通讯作者：
RanckJr,JB
中科院分区：
文献类型：
--
作者：
Best,PJ;RanckJr,JB
海马细胞活动与行为的关系通过制作记录过程的录像带进行评估，这些录像带对大鼠的各种行为进行采样。单元信号通过分屏设备显示在画面的上四分之一。一个单元的输出在磁带的音频通道上呈现。这些录像带随后被展示给天真的观察者，他们记录了与快速或缓慢细胞活动相关的行为。观察者还被要求对每个细胞的活动和行为之间的关系得出结论，并说明他们对结论的信心水平。制作了23个磁带，14个海马复合锋电位细胞，5 θ细胞，1个丘脑细胞，和3个对照磁带，其中一个会话的复合锋电位活动与另一个会话的行为一起呈现。观察员对大多数单元表现出高度的信任和强烈的一致性。在15个复合棘细胞中，9个被判断为与动物在空间中的位置有关，2个与旋转运动有关，1个与饮水有关。5 θ细胞都与一般运动有关。学生们发现2个复杂的棘细胞、丘脑细胞和3个对照带没有令人信服的感觉行为相关性。结果表明，海马细胞活动与动物在空间中的位置的关系比与J. Ranck（1973，Exp. 41：461-531）。这项研究还表明，通过向大量观察者展示行为磁带，可以在观察方法中获得高度的可靠性。
The relationship of hippocampal cellular activity to behavior was assessed by making videotapes of recording sessions which sampled a variety of behaviors in the rat. The unit signals were displayed via a split screen device on the upper one-quarter of the picture. The output of a unit discriminator was presented on the audio channel of the tape. The tapes were later presented to naive observers who kept a running account of the behaviors correlated with fast or slow cell activity. The observers were also instructed to draw conclusions about the relationship between each cell's activity and behavior, and to state their confidence level in their conclusions. Twenty-three tapes were made, 14 hippocampal complex spike cells, 5 theta cells, one thalamic cell, and 3 control tapes in which complex spike activity from one session was presented with behaviors of another session. The observers showed high confidence and strong agreement on most of the cells. Of the 15 complex spike cells, 9 were judged to be related to the animal's position in space, 2 were related to turning movement, and 1 to drinking. The 5 theta cells were all related to general movement. The students found no compelling sensory behavioral correlates for 2 complex spike cells, the thalamic cell, and the 3 control tapes. The results indicate that hippocampal cellular activity is much more related to an animal's position in space than to the variety of sensory behavioral events previously described by J. Ranck (1973,Exp. Neurol.41:461–531). The study also shows that a high degree of reliability can be obtained in the observational approach by the presentation of tapes of behavior to a large number of observers.
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发表时间：
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期刊：
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DOI：
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DOI：
--
发表时间：
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期刊：
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