Validation of maternal reports for low birthweight and preterm birth indicators in rural Nepal.

Validation of maternal reports for low birthweight and preterm birth indicators in rural Nepal.
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DOI:
10.7189/jogh.08.010604
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发表时间:
2018-06
影响因子:
7.2
通讯作者:
Katz J
Katz J
中科院分区:
医学2区
文献类型:
--
作者:
Chang KT;Mullany LC;Khatry SK;LeClerq SC;Munos MK;Katz J

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跟踪实现全球新生儿健康目标的进展情况在很大程度上取决于通过具有全国代表性的大型调查收集的孕产妇报告数据。我们评估了在一系列回忆期长度(产后1至24个月)内,母亲报告出生体重、出生大小和妊娠时间的有效性。我们将母体报告与分娩后72小时内测量的出生体重和末次月经第一天(LMP)报告的胎龄的参考标准进行了比较,这些参考标准是前瞻性收集的,作为基于人群的研究的一部分(n = 1502)。我们计算了灵敏度、特异性、受试者工作曲线下面积(AUC)作为个体水平准确性的衡量指标,并计算了膨胀因子(IF)来量化每个指标的人群水平偏倚。我们评估了回忆期的长度是否会改变准确性,方法是将测量值跨时间箱分层,并使用具有稳健误差方差的改良泊松回归来估计正确将新生儿分类为低出生体重(LBW)或早产的相对风险(RR),调整儿童性别,分娩地点,母亲年龄,母亲教育程度,产次和种族。使用母亲报告的出生体重(克)的LBW指标具有较低的个体水平准确性(AUC = 0.69)和较高的人群水平偏倚(膨胀因子IF = 0.62)。使用母亲报告的出生大小和早产指标的LBW在出生后24个月内具有较低的个体水平准确性(AUC分别为0.58和0.56)和较高的群体水平偏倚(IF分别为0.28和0.35)。回忆时间的长短并不影响LBW指标的准确性。对于早产指标,准确性在出生后20个月内没有随着回忆时间的推移而变化,并在20个月后略有改善。使用产妇报告可能会低估和偏差指标的出生体重不足和早产。在低出生体重和早产发生率高的情况下,从孕产妇报告中产生的这些指标可能更容易被错误分类。在大部分出生在家中或不经常测量体重的人群中,母亲可能不太重视记住出生时的尺寸。需要进一步的工作,以探讨是否这些结论的有效性孕产妇报告举行类似的农村和低收入环境。
Tracking progress towards global newborn health targets depends largely on maternal reported data collected through large, nationally representative surveys. We evaluated the validity, across a range of recall period lengths (1 to 24 months post-delivery), of maternal report of birthweight, birth size and length of pregnancy. We compared maternal reports to reference standards of birthweights measured within 72 hours of delivery and gestational age generated from reported first day of the last menstrual period (LMP) prospectively collected as part of a population-based study (n = 1502). We calculated sensitivity, specificity, area the under the receiver operating curve (AUC) as a measure of individual-level accuracy, and the inflation factor (IF) to quantify population-level bias for each indicator. We assessed if length of recall period modified accuracy by stratifying measurements across time bins and using a modified Poisson regression with robust error variance to estimate the relative risk (RR) of correctly classifying newborns as low birthweight (LBW) or preterm, adjusting for child sex, place of delivery, maternal age, maternal education, parity, and ethnicity. The LBW indicator using maternally reported birthweight in grams had low individual-level accuracy (AUC = 0.69) and high population-level bias (inflation factor IF = 0.62). LBW using maternally reported birth size and the preterm birth indicator had lower individual-level accuracy (AUC = 0.58 and 0.56, respectively) and higher population-level bias (IF = 0.28 and 0.35, respectively) up to 24 months following birth. Length of recall time did not affect accuracy of LBW indicators. For the preterm birth indicator, accuracy did not change with length of recall up to 20 months after birth and improved slightly beyond 20 months. The use of maternal reports may underestimate and bias indicators for LBW and preterm birth. In settings with high prevalence of LBW and preterm births, these indicators generated from maternal reports may be more vulnerable to misclassification. In populations where an important proportion of births occur at home or where weight is not routinely measured, mothers perhaps place less importance on remembering size at birth. Further work is needed to explore whether these conclusions on the validity of maternal reports hold in similar rural and low-income settings.
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发表时间: 2008-06
期刊: BJOG : an international journal of obstetrics and gynaecology
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