The Effect of Discrimination on Likelihood of Participation in a Clinical Trial.
The Effect of Discrimination on Likelihood of Participation in a Clinical Trial.
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DOI：
10.1007/s40615-020-00735-5
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发表时间：
2020-12
影响因子：
3.9
通讯作者：
Fisher S
中科院分区：
文献类型：
--
作者：
Devlin A;Gonzalez E;Ramsey F;Esnaola N;Fisher S
尽管努力增加少数族裔参加研究的人数，但种族差异仍然存在，人们仍然认为少数族裔天生就不太可能参加医学研究。这种挥之不去的观点可能会影响向少数族裔患者展示研究的方式。这项研究旨在评估在寻求医疗护理时报告的歧视的种族差异以及参与医学研究研究的可能性。844名居民通过便利抽样进行登记，并被要求完成一项旨在检查在寻求医疗保健时感觉到的歧视和参与医学研究的可能性(LOP)的调查。报告比其他种族待遇更差的参与者的平均LOP得分(53.7±17.6)低于报告受到同等待遇的参与者(61.1±16.1)或优于其他种族(64.0±15.0)的参与者(p<；.001)。不同种族/民族的LOP平均得分没有显著差异。种族与歧视的交互作用对平均LOP没有显著影响(p=0.8)。尽管大多数参与者报告没有歧视，但种族和歧视之间存在统计上的显著关联(X2=11.32，p=0.023)。患者在医学领域的经历可能会影响他们加入医学研究的意愿。增加少数群体参与研究的一个有效策略可能是与研究人员和工作人员合作，解决与少数群体患者有关的隐性偏见。进一步的研究应侧重于研究人员互动对个人决策过程的影响。
Despite efforts to increase minority enrollment in research, racial disparities still exist and a belief persists that minorities are inherently less likely to enroll in medical research. This lingering view may impact the manner in which studies are presented to minority patients. This study aimed to assess racial differences in reported discrimination while seeking medical care and likelihood to participate in a medical research study. 844 residents were enrolled via convenience sampling, and asked to complete a survey designed to examine perceived discrimination while seeking healthcare and likelihood to participate (LoP) in a medical research study. Participants who reported worse treatment than other races had lower mean LoP scores (53.7 ± 17.6) than participants who reported being treated the same as (61.1 ± 16.1) or better than (64.0 ± 15.0) other races (p < .001). There were no significant differences in mean LoP score by race/ethnicity. The interaction of race with discrimination had no significant effect on mean LoP (p = 0.8). There was a statistically significant association between race and discrimination (X2 = 11.32, p = 0.023), although the majority of participants reported no discrimination. Patient experiences in the medical arena may have an impact on their willingness to join a medical study. An effective strategy to increase minority participation in research may be to work with investigators and staff on implicit bias with regards to minority patients. Further research should focus on the impact of research staff interactions on an individual’s decision-making process.
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影响因子：
2.2
作者：
Tanner, Andrea;Kim, Sei-Hill;Bergeron, Caroline D.
通讯作者：
Bergeron, Caroline D.
DOI：
10.1016/0197-2456(95)00048-8
发表时间：
1995-10-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
FREEDMAN, LS;SIMON, R;MOWERY, R
通讯作者：
MOWERY, R
影响因子：
3
作者：
Armstrong K;Putt M;Halbert CH;Grande D;Schwartz JS;Liao K;Marcus N;Demeter MB;Shea JA
通讯作者：
Shea JA
影响因子：
12.7
作者：
Purnell, Jason Q.;Peppone, Luke J.;Morrow, Gary R.
通讯作者：
Morrow, Gary R.
影响因子：
1.4
作者：
Scharff, Darcell P.;Mathews, Katherine J.;Edwards, Dorothy
通讯作者：
Edwards, Dorothy