Determinants of left ventricular aneurysm formation after anterior myocardial infarction: a clinical and angiographic study.
Determinants of left ventricular aneurysm formation after anterior myocardial infarction: a clinical and angiographic study.
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前壁心肌梗死后左心室动脉瘤形成的决定因素：临床和血管造影研究。
DOI：
10.1016/s0735-1097(86)80294-7
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发表时间：
1986
影响因子：
24
通讯作者：
Friesinger,GC
中科院分区：
文献类型：
--
作者：
Forman,MB;Collins,HW;Kopelman,HA;Vaughn,WK;Perry,JM;Virmani,R;Friesinger,GC
为确定透壁性前壁心肌梗死后左室壁瘤形成的相关因素，对79例首次心肌梗死患者进行了评估，这些患者在梗死后6个月内接受了心导管检查。排除接受过溶栓治疗的患者。根据左前降支动脉的状态和是否存在左心室动脉瘤将患者分为4组：I组（n = 25）：动脉瘤伴左前降支动脉闭塞; II组（n = 27）：无动脉瘤伴左前降支动脉闭塞; HI组（n = 23）：无动脉瘤伴左前降支动脉通畅;第四组（n = 4）：动脉瘤合并左前降支开放，单支病变在第一组（动脉瘤）比第二组和第三组（无动脉瘤）更常见（x ~（42）= 12.8;概率值等于0.012）。与II组（无动脉瘤）相比，I组（动脉瘤）中存在闭塞的左前降支动脉时的侧支血供明显较少（0.9 vs 2.4，p < 0.001）。第I组和第II组的冠状动脉疾病程度和侧支供血直接相关（p = 0.012）。年龄、性别和冠心病危险因素均与动脉瘤形成无关。在平均48个月的随访中，在复发性心绞痛、新发心肌梗死、栓塞事件或猝死的发生率方面没有观察到差异。II组中更多的患者接受了冠状动脉搭桥手术，左前降支完全闭塞与固有的侧支供血不足是前壁心肌梗死后动脉瘤形成的重要决定因素。多支血管病变伴侧支循环良好或左前降支动脉开放者，不常发生左室壁瘤。
To determine factors involved in left ventricular aneurysm formation after transmural anterior myocardial infarction, 79 patients with a first myocardial infarction who underwent cardiac catheterization within 6 months of infarction were evaluated. Patients who had received thrombolytic therapy were excluded. Patients were divided into four groups depending on the status of the left anterior descending artery and the presence or absence of a left ventricular aneurysm: Group I (n = 25): aneurysm with occluded left anterior descending artery; Group II (n = 27): no aneurysm and occluded left anterior descending artery; Group HI (n = 23): no aneurysm and patent left anterior descending artery; and Group IV (n = 4): aneurysm with patent left anterior descending artery.Single vessel disease was more common in Group I (aneurysm) compared with Groups II and III (no aneurysm) (x42= 12.8; probability value equal to 0.012). Collateral blood supply in the presence of an occluded left anterior descending artery was significantly less in Group I (aneurysm) compared with Group II (no aneurysm) (0.9 versus 2.4, p < 0.001). The extent of coronary artery disease and collateral blood supply in Groups I and II were directly related (p = 0.012). Neither age, sex nor risk factors for coronary disease correlated with aneurysm formation. At a mean follow-up of 48 months, no differences were observed in the incidence of recurrent angina, new myocardial infarction, embolic events or sudden death. More patients in Group II underwent coronary artery bypass surgery.Total occlusion of the left anterior descending artery in association with inherent poor collateral blood supply is a significant determinant of aneurysm formation after anterior myocardial infarction. Multivessel disease with either good collateral circulation or a patent left anterior descending artery is uncommonly associated with the development of left ventricular aneurysm.
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影响因子：
37.8
作者：
M. Forman;S. Bingham;H. Kopelman;C. Wehr;M. Sandler;F. Kolodgie;W. Vaughn;G. Friesinger;R. Virmani
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影响因子：
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作者：
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H. Abe
室动脉瘤修复后的临床改善：通过血管造影和血流动力学变量进行预测。
影响因子：
24
作者：
S. Kiefer;G. Flaker;R. Martin;J. Curtis
通讯作者：
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影响因子：
9
作者：
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C. Hatcher