Longitudinal Study of HTLV‐III‐Infected Chimpanzees by Lymphocyte Subpopulation Analysis
Longitudinal Study of HTLV‐III‐Infected Chimpanzees by Lymphocyte Subpopulation Analysis
复制标题
通过淋巴细胞亚群分析对 HTLV-III 感染的黑猩猩进行纵向研究
DOI：
10.1111/j.1600-0684.1985.tb00272.x
复制
发表时间：
1985
影响因子：
0.7
通讯作者：
G. R. Dreesman
中科院分区：
文献类型：
--
作者：
J. Eichberg;H. Alter;G. R. Dreesman
用人类艾滋病患者的血浆接种后，两只黑猩猩表现出特异性的抗人T细胞白血病病毒3型(HTLV-III)抗体。两只黑猩猩中的一只还出现了持续32周的大规模淋巴结病，表现出总T细胞(T3)和辅助性T细胞(T4)同时更频繁地受到抑制，T4与T抑制细胞(T8)的比率下降。这些结果表明，在HTLV-III引起的感染和疾病期间，黑猩猩表现出一系列的T细胞亚群。
Following inoculation with plasma from human patients with AIDS, two chimpanzees demonstrated specific antihuman T‐cell leukemia virus type 3 (HTLV‐III) antibodies. One of the two chimpanzees also developed massive lymphadenopathy that persisted for 32 weeks and demonstrated a concurrent and more frequent depression of total T cells (T3) and T helper cells (T4) with a decrease in the ratios of T4 to T suppressor cells (T8). These results indicate that chimpanzees demonstrate a range of T‐cell subpopulations during infection and disease induced by HTLV‐III.
使用 T 细胞子集分析对患有获得性免疫缺陷综合征的患者进行的纵向研究。
影响因子：
--
作者：
Siegel,RL;Fox,RW
通讯作者：
Fox,RW