Quantitative sonoelastography for the in vivo assessment of skeletal muscle viscoelasticity.
Quantitative sonoelastography for the in vivo assessment of skeletal muscle viscoelasticity.
复制标题
用于体内骨骼肌肉粘弹性体内评估的定量声弹性学。
DOI：
10.1088/0031-9155/53/15/004
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发表时间：
2008-08-07
影响因子：
3.5
通讯作者：
Parker KJ
中科院分区：
文献类型：
--
作者：
Hoyt K;Kneezel T;Castaneda B;Parker KJ
建立了一种新的定量超声弹性成像技术，用于评估骨骼肌组织的粘弹性。缓慢传播的剪切波干涉图案（称为爬行波）产生使用两个源配置垂直于表面振动。理论模型预测了爬行波位移场，并通过体模研究进行了验证。在实验中，粘弹性模型适合色散剪切波速度sonoelastographic数据，使用非线性最小二乘技术，以确定与频率无关的剪切模量和粘度估计。使用粘弹性模型得出的剪切模量估计值与通过对体模样本进行机械测试获得的结果一致。在健康人体骨骼肌中获得的初步声弹性成像数据证实，可以在体内获得高质量的定量弹性数据。松弛肌肉的研究表明，不同骨骼肌群之间的剪切模量和粘度估计值存在明显差异。对（健康）人体骨骼肌动态粘弹特性的研究表明，与放松状态相比，自愿收缩的肌肉的剪切模量和粘度估计值都显着增加。总体而言，初步结果是令人鼓舞的，定量超声弹性成像可能证明在临床上可行的人体骨骼肌的动态粘弹性特性的体内表征。
A novel quantitative sonoelastography technique for assessing the viscoelastic properties of skeletal muscle tissue was developed. Slowly propagating shear wave interference patterns (termed crawling waves) were generated using a two-source configuration vibrating normal to the surface. Theoretical models predict crawling wave displacement fields, which were validated through phantom studies. In experiments, a viscoelastic model was fit to dispersive shear wave speed sonoelastographic data using nonlinear least-squares techniques to determine frequency-independent shear modulus and viscosity estimates. Shear modulus estimates derived using the viscoelastic model were in agreement with that obtained by mechanical testing on phantom samples. Preliminary sonoelastographic data acquired in healthy human skeletal muscles confirm that high-quality quantitative elasticity data can be acquired in vivo. Studies on relaxed muscle indicate discernible differences in both shear modulus and viscosity estimates between different skeletal muscle groups. Investigations into the dynamic viscoelastic properties of (healthy) human skeletal muscles revealed that voluntarily contracted muscles exhibit considerable increases in both shear modulus and viscosity estimates as compared to the relaxed state. Overall, preliminary results are encouraging and quantitative sonoelastography may prove clinically feasible for in vivo characterization of the dynamic viscoelastic properties of human skeletal muscle.
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影响因子：
2.4
作者：
MADSEN, EL;SATHOFF, HJ;ZAGZEBSKI, JA
通讯作者：
ZAGZEBSKI, JA
影响因子：
2.4
作者：
OESTREICHER, HL
通讯作者：
OESTREICHER, HL
影响因子：
4.3
作者：
Basford, JR;Jenkyn, TR;Kaufman, KR
通讯作者：
Kaufman, KR
DOI：
10.1109/58.251284
发表时间：
1993-07-01
影响因子：
3.6
作者：
HETE, B;SHUNG, KK
通讯作者：
SHUNG, KK
影响因子：
2.4
作者：
HUANG, SR;LERNER, RM;PARKER, KJ
通讯作者：
PARKER, KJ