IDT SciTools: a suite for analysis and design of nucleic acid oligomers.
IDT SciTools: a suite for analysis and design of nucleic acid oligomers.
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IDT Scitools:用于分析和设计核酸低聚物的套件。
DOI:
10.1093/nar/gkn198
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发表时间:
2008-07-01
影响因子:
14.9
通讯作者:
Peek AS
中科院分区:
文献类型:
--
作者:
Owczarzy R;Tataurov AV;Wu Y;Manthey JA;McQuisten KA;Almabrazi HG;Pedersen KF;Lin Y;Garretson J;McEntaggart NO;Sailor CA;Dawson RB;Peek AS
DNA and RNA oligomers are used in a myriad of diverse biological and biochemical experiments. These oligonucleotides are designed to have unique biophysical, chemical and hybridization properties. We have created an integrated set of bioinformatics tools that predict the properties of native and chemically modified nucleic acids and assist in their design. Researchers can select PCR primers, probes and antisense oligonucleotides, find the most suitable sequences for RNA interference, calculate stable secondary structures, and evaluate the potential for two sequences to interact. The latest, most accurate thermodynamic algorithms and models are implemented. This free software is available at http://www.idtdna.com/SciTools/SciTools.aspx.
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DOI:
10.1073/pnas.77.11.6309
发表时间:
1980-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
--
作者:
NUSSINOV, R;JACOBSON, AB
通讯作者:
JACOBSON, AB
影响因子:
14.9
作者:
Cavaluzzi, MJ;Borer, PN
通讯作者:
Borer, PN
影响因子:
2.9
作者:
MARKY, LA;BRESLAUER, KJ
通讯作者:
BRESLAUER, KJ
影响因子:
9.5
作者:
Olson, Sue A
通讯作者:
Olson, Sue A
影响因子:
2.9
作者:
Allawi, HT;SantaLucia, J
通讯作者:
SantaLucia, J