Race-based medical mistrust, medication beliefs and HIV treatment adherence: test of a mediation model in people living with HIV/AIDS.
Race-based medical mistrust, medication beliefs and HIV treatment adherence: test of a mediation model in people living with HIV/AIDS.
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DOI：
10.1007/s10865-016-9767-1
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发表时间：
2016-12
影响因子：
3.1
通讯作者：
Welles, Brandi
中科院分区：
文献类型：
--
作者：
Kalichman, Seth C.;Eaton, Lisa;Kalichman, Moira O.;Grebler, Tama;Merely, Cynthia;Welles, Brandi
基于种族的医疗不信任显著预测艾滋病毒携带者不坚持抗逆转录病毒疗法(ART)。目前的研究建立在之前的研究基础上，这些研究表明，关于药物必要性(即，“我的药物保护我不会变得更糟”)和担忧(即，不得不服用我的药物让我担心)的信念在基于种族的医疗不信任和坚持用药之间起到了中介作用。在美国南部一座城市，携带艾滋病毒并接受抗逆转录病毒治疗(N=178)的少数族裔男性和女性完成了人口和健康特征的计算机化测量，对基于种族的医疗不信任和药物信念进行了电话采访，并对坚持抗逆转录病毒治疗的未公布电话药片计数进行了研究。多元中介模型显示，医疗不信任与用药必要性和关注度、信念和艺术坚持有关。此外，药物必需性信念预示着ART的依从性。医疗不信任通过药物必要性信念对坚持的间接影响也是显著的。结果证实，尽管与信念无关，但药物必要性信念在医疗不信任和ART依从性之间起中介作用。药物必要性信念为在患者可能对医疗提供者和卫生保健系统存在不信任的情况下改善抗逆转录病毒治疗依从性的干预提供了一个可行的目标。
Race-based medical mistrust significantly predicts non-adherence to antiretroviral therapy (ART) in people living with HIV. The current study builds on previous research that shows beliefs about medication necessity (i.e., “My medicines protect me from becoming worse”) and concerns (i.e., Having to take my medicines worries me) mediate the association between race-based medical mistrust and medication adherence. Racial and ethnic minority men and women living with HIV and receiving ART (N=178) in a southern US city completed computerized measures of demographic and health characteristics, telephone interviews of race-based medical mistrust and medication beliefs, and unannounced phone-based pill counts for ART adherence. Multiple mediation modeling showed that medical mistrust is related to medication necessity and concerns beliefs and ART adherence. Furthermore, medication necessity beliefs predicted ART adherence. The indirect effect of medical mistrust on adherence through medication necessity beliefs was also significant. Results confirm that medication necessity beliefs, although not concerns beliefs, mediate the association between medical mistrust and ART adherence. Medication necessity beliefs offer a viable target for interventions to improve ART adherence in the context of mistrust that patients may have for medical providers and health care systems.
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影响因子：
4.4
作者：
Haberer, Jessica E.;Robbins, Gregory K.;Ybarra, Michele;Monk, Alexandra;Ragland, Kathleen;Weiser, Sheri D.;Johnson, Mallory O.;Bangsberg, David R.
通讯作者：
Bangsberg, David R.
影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
DOI：
10.1097/qai.0b013e3182a095e9
发表时间：
2013-11-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
McFall AM;Dowdy DW;Zelaya CE;Murphy K;Wilson TE;Young MA;Gandhi M;Cohen MH;Golub ET;Althoff KN;Women's Interagency HIV Study
通讯作者：
Women's Interagency HIV Study
影响因子：
16.4
作者：
Pellowski, Jennifer A.;Kalichman, Seth C.;Matthews, Karen A.;Adler, Nancy
通讯作者：
Adler, Nancy
影响因子：
4.4
作者：
Nozaki, Ikuma;Kuriyama, Mika;Manyepa, Pauline;Zyambo, Matilda K.;Kakimoto, Kazuhiro;Baernighausen, Till
通讯作者：
Baernighausen, Till