Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related dideoxynucleosides.
Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related dideoxynucleosides.
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3-叠氮基-2,3-二脱氧胸苷(齐多夫定)和相关双脱氧核苷的临床药理学。
DOI:
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发表时间:
1989
影响因子:
158.5
通讯作者:
S. Broder
中科院分区:
文献类型:
--
作者:
R. Yarchoan;H. Mitsuya;C. Myers;S. Broder
THE development of a rational therapy against the etiologic agent of the acquired immunodeficiency syndrome (AIDS)1 2 3 was made possible by the discovery that a cytopathic retrovirus, now called the human immunodeficiency virus (HIV), caused the disorder.4 5 6 This discovery and the ability to grow the virus in large quantities made possible the development of in vitro techniques to find drugs that inhibit the replication of HIV.7 , 8 Substances that acted against HIV in vitro were identified for further study, and the practical development of drugs thus proceeded. The work was in part an outgrowth of early research on animal retroviral systems in . . .
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影响因子:
56.9
作者:
Gary J. Nabel;Stephen A. Rice;D. Knipe;D. Baltimore
通讯作者:
Gary J. Nabel;Stephen A. Rice;D. Knipe;D. Baltimore
DOI:
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发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Cheng,YC;Dutschman,GE;Bastow,KF;Sarngadharan,MG;Ting,RY
通讯作者:
Ting,RY
DOI:
--
发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Starnes,MC;Cheng,YC
通讯作者:
Cheng,YC
DOI:
10.1126/science.2847316
发表时间:
1988
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Till,MA;Ghetie,V;Gregory,T;Patzer,EJ;Porter,JP;Uhr,JW;Capon,DJ;Vitetta,ES
通讯作者:
Vitetta,ES
影响因子:
56.9
作者:
LARDER, BA;DARBY, G;RICHMAN, DD
通讯作者:
RICHMAN, DD