Diagnostic transvitreal fine-needle aspiration biopsy of small melanocytic choroidal tumors in nevus versus melanoma category.
Diagnostic transvitreal fine-needle aspiration biopsy of small melanocytic choroidal tumors in nevus versus melanoma category.
复制标题
痣与黑色素瘤类别中小型黑色素细胞脉络膜肿瘤的诊断性经玻璃体细针抽吸活检。
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
N. Trichopoulos
中科院分区：
文献类型：
--
作者：
J. Augsburger;Z. Corrêa;S. Schneider;Rawia S. Yassin;Toni M. Robinson;H. Ehya;N. Trichopoulos
目的
报告1983年4月13日至2001年1月19日期间对选定的小黑色素细胞脉络膜肿瘤进行细针穿刺活检的经验。
方法
回顾性描述性病例系列报告，34例小黑色素细胞脉络膜肿瘤（最大直径≤ 10 mm;厚度≥ 1.5 mm但≤ 3 mm）患者在治疗前通过经玻璃体细针穿刺活检进行诊断评估。所有肿瘤在活检时均无侵袭性特征。
结果
患者年龄范围为26 - 73岁（平均50.9岁）。评估脉络膜肿瘤的平均最大基底直径为8.0 mm，平均最大厚度为2.4 mm。34个肿瘤中有18个（52.9%）在活检前被记录为扩大。所有病例均使用25号中空腔穿刺针和经睫状体平坦部穿刺部位的经玻璃体途径进行活检。34例中有22例（64.7%）的穿刺活检获得了足够的细胞学诊断。其中恶性黑色素瘤16例（47.1%），中间型4例（11.8%），良性痣2例（5.9%）。12个肿瘤产生了不充分的抽吸和4个病变产生中间细胞继续被归类为“痣与黑色素瘤”，并定期监测生长或其他变化。12个肿瘤中的4个产生了不足以进行细胞诊断的抽吸物，所有4个产生中间细胞的病变最终被重新分类为小脉络膜黑色素瘤并进行治疗。在最近的随访评价中，剩余的8个肿瘤产生的抽吸物不足，2个肿瘤产生的良性痣细胞被归类为良性痣。
结论
细针穿刺活检显示，很大一部分小的黑色素细胞脉络膜肿瘤可能在临床上被归类为小脉络膜黑色素瘤在许多中心，实际上是良性痣或中间病变。
PURPOSE
To report an experience with fine-needle aspiration biopsy of selected small melanocytic choroidal tumors during the interval from April 13, 1983, through January 19, 2001.
METHODS
Retrospective descriptive case series report of 34 patients with a small melanocytic choroidal tumor (maximal diameter, < or = 10 mm; thickness, > or = 1.5 mm but < or = 3 mm) evaluated diagnostically by transvitreal fine-needle aspiration biopsy prior to treatment. None of the tumors had invasive features at the time of biopsy.
RESULTS
Patients ranged in age from 26 to 73 years (mean, 50.9 years). The evaluated choroidal tumors had a mean maximal basal diameter of 8.0 mm and a mean maximal thickness of 2.4 mm. Eighteen of the 34 tumors (52.9%) had been documented to enlarge prior to biopsy. Biopsy was performed in all cases using a 25-gauge hollow lumen needle and a transvitreal approach via a pars plana puncture site. The biopsy yielded a sufficient aspirate for cytodiagnosis in 22 of 34 cases (64.7%). In these cases, the tumor was classified as malignant melanoma in 16 (47.1% of total), intermediate lesion in 4 (11.8%), and benign nevus in 2 (5.9%). The 12 tumors that yielded an insufficient aspirate and the four lesions that yielded intermediate cells continued to be classified as "nevus versus melanoma" and were monitored periodically for growth or other changes. Four of the 12 tumors that yielded an insufficient aspirate for cytodiagnosis and all four lesions that yielded intermediate cells were eventually reclassified as small choroidal melanomas and treated. The remaining eight tumors that yielded an insufficient aspirate and the two tumors that yielded benign nevus cells were classified as benign nevi at the most recent follow-up evaluation.
CONCLUSIONS
Fine-needle aspiration biopsy showed that a substantial proportion of small melanocytic choroidal tumors likely to be classified clinically as small choroidal melanomas in many centers were in fact benign nevi or intermediate lesions.
经瞳孔热疗治疗小脉络膜黑色素瘤。
影响因子：
4.2
作者：
Godfrey,DG;Waldron,RG;CaponeJr,A
通讯作者：
CaponeJr,A