Transpupillary thermotherapy for small choroidal melanoma.
Transpupillary thermotherapy for small choroidal melanoma.
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经瞳孔热疗治疗小脉络膜黑色素瘤。
DOI：
10.1016/s0002-9394(99)00063-x
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发表时间：
1999
影响因子：
4.2
通讯作者：
CaponeJr,A
中科院分区：
文献类型：
--
作者：
Godfrey,DG;Waldron,RG;CaponeJr,A
METHODS为了报告小脉络膜黑色素瘤的治疗与transpupillary thermotherapy. METHODS我们检查了一个非随机和对照系列的14眼14例患者进行了后续的系列眼底镜检查，超声检查和摄影。经瞳孔温热疗法后，平均随访时间± SD为16 ± 6.41个月（范围，7至28个月），其中10只眼随访至少1年。平均术前肿瘤高度为1.79 ± 0.59 mm（范围：0.78 - 2.60 mm）。治疗后6个月，平均身高为0.54 mm ± 0.57 mm（范围：0.00 - 1.16 mm）。在10只眼中，治疗后的病变完全变平，治疗和变平之间的平均间隔为8.7个月（范围，3至21个月）。3例患者因缺乏消退或复发性生长而需要再次治疗。至再次治疗的平均时间为11个月（范围：5至15个月）。没有一只眼睛后退超过一次。有三个无色素病变，所有治疗在一个单一的会议没有复发。并发症包括视网膜出血、视网膜血管阻塞、视网膜牵拉、渗出性浆液性感觉神经脱离、玻璃体炎和术后疼痛。唯一的治疗失败发生在一只接受过乳头状肿瘤治疗的眼睛中，复发是由先前的扁平病变引起的。该眼在单次初始治疗后10个月摘除。在撰写本文时，没有肿瘤相关的death.CONCLUSIONSTranspupillary热疗法可能是色素性和无色素性小脉络膜黑色素瘤的一种可行的治疗选择。勤奋的后续行动是不言自明的，因为可能需要再治疗。复发性肿瘤可能由扁平病灶发展而来。乳头旁肿瘤复发的风险可能更高。关于经瞳孔温热疗法在小脉络膜黑色素瘤治疗中的作用，有待5年和10年的发病率和死亡率数据的证实。
PURPOSETo report the treatment of small choroidal melanoma with transpupillary thermotherapy.METHODSWe examined a nonrandomized and uncontrolled series of 14 eyes of 14 patients who were followed up with serial ophthalmoscopy, ultrasonography, and photography. Transpupillary thermotherapy was performed upon documented evidence of tumor growth.RESULTSAfter transpupillary thermotherapy, mean follow-up ± SD was 16 ± 6.41 months (range, 7 to 28 months) with 10 eyes followed up for at least 1 year. The mean preoperative tumor height was 1.79 ± 0.59 mm (range, 0.78 to 2.60 mm). Six months after treatment, the mean height was 0.54 mm ± 0.57 mm (range, 0.00 to 1.16 mm). In 10 eyes, the treated lesion flattened entirely with a mean interval between treatment and flattening of 8.7 months (range, 3 to 21 months). Three patients required retreatment for lack of regression or recurrent growth. The average time to retreatment was 11 months (range, 5 to 15 months). No eye was retreated more than once. There were three amelanotic lesions, all treated in a single session without recurrence. Complications consisted of retinal hemorrhage, retinal vascular occlusion, retinal traction, exudative serous neurosensory detachment, vitreitis, and postoperative pain. The sole treatment failure occurred in an eye treated with a juxtapapillary tumor, with recurrence developing from a previously flattened lesion. This eye was enucleated 10 months after the single initial treatment. At the time of writing, there had been no tumor-related death.CONCLUSIONSTranspupillary thermotherapy may represent a viable treatment alternative for both pigmented and amelanotic small choroidal melanoma. Diligent follow-up is axiomatic because retreatment may be necessary. Recurrent tumors may develop from flat lesions. Juxtapapillary tumors may be at higher risk for recurrence. Definitive statements regarding the role of transpupillary thermotherapy in the management of small choroidal melanoma await 5-year and 10-year morbidity and mortality data.
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小脉络膜黑色素瘤生长和治疗的预测因素：COMS 报告第 5 号。眼部黑色素瘤协作研究组。
DOI：
10.1001/archopht.1997.01100160707007
发表时间：
1997
期刊：
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子：
--
作者：
通讯作者：
--
影响因子：
4.2
作者：
B. Hawkins;A. K. Vine;J. Willis;B. Frueh;R. Kurtz;S. Elner;M. W. Johnson;S. Sneed;J. Hayman;A. Lichter;C. Mcginn;J. Robertson;S. Schoeppel;R. T. Haken;A. Thompson;K. A. Meyer;C. Mártonyi;S. Stanley;V. Elner;M. Kincaid;R. J. Wolter;P. Sternberg;J. M. Brown;T. Aaberg;A. Capone;T. Wojno;Jennifer I. Lim;J. Keller;J. Landry;I. Crocker;J. McLaren;C. A. Aguilera;E. Butker;K. A. Klee;D. Strongosky;D. Gibbs;L. T. Curtis;A. Fremstad;R. Waldron;A. Ward;J. Gilman;R. Myles;R. Swords;H. Grossniklaus;F. Calhoun;W. Campbell;W. H. Jarrett;W. Hagler;R. L. Halpern;N. Jones;F. Schwaibold;K. Wynn;P. Mondalek;G. Degenhardt;E. Hulsey;D. H. Lee;J. Aaron;D. Bolerjak;S. Mccart;G. McCoy;K. D. Thompson;B. Baxter;B. Robinson;K. Wilson;A. Schachat;W. Doll;E. F. Greenberg;M. Alexander;C. Sackett;M. Goldberg;L. Hammer;N. Iliff;D. J. Lee;M. Chun;J. F. Jackson;J. Iannito;W. C. Lam;L. Pollack;C. Dibernardo;D. Cain;D. Emmert;T. George;Z. Zakov;T. A. Rice;M. Hartnett;S. Lichterman;K. Dempsey;D. Preseren;J. Niffenegger;M. A. Novak;S. Pendergast;L. J. Singermann;D. Weidenthal;H. Zegarra;J. Antoszyk;D. Shina;K. Pillai;D. Knight;K. Coreno
通讯作者：
B. Hawkins;A. K. Vine;J. Willis;B. Frueh;R. Kurtz;S. Elner;M. W. Johnson;S. Sneed;J. Hayman;A. Lichter;C. Mcginn;J. Robertson;S. Schoeppel;R. T. Haken;A. Thompson;K. A. Meyer;C. Mártonyi;S. Stanley;V. Elner;M. Kincaid;R. J. Wolter;P. Sternberg;J. M. Brown;T. Aaberg;A. Capone;T. Wojno;Jennifer I. Lim;J. Keller;J. Landry;I. Crocker;J. McLaren;C. A. Aguilera;E. Butker;K. A. Klee;D. Strongosky;D. Gibbs;L. T. Curtis;A. Fremstad;R. Waldron;A. Ward;J. Gilman;R. Myles;R. Swords;H. Grossniklaus;F. Calhoun;W. Campbell;W. H. Jarrett;W. Hagler;R. L. Halpern;N. Jones;F. Schwaibold;K. Wynn;P. Mondalek;G. Degenhardt;E. Hulsey;D. H. Lee;J. Aaron;D. Bolerjak;S. Mccart;G. McCoy;K. D. Thompson;B. Baxter;B. Robinson;K. Wilson;A. Schachat;W. Doll;E. F. Greenberg;M. Alexander;C. Sackett;M. Goldberg;L. Hammer;N. Iliff;D. J. Lee;M. Chun;J. F. Jackson;J. Iannito;W. C. Lam;L. Pollack;C. Dibernardo;D. Cain;D. Emmert;T. George;Z. Zakov;T. A. Rice;M. Hartnett;S. Lichterman;K. Dempsey;D. Preseren;J. Niffenegger;M. A. Novak;S. Pendergast;L. J. Singermann;D. Weidenthal;H. Zegarra;J. Antoszyk;D. Shina;K. Pillai;D. Knight;K. Coreno
DOI：
--
发表时间：
1989
期刊：
Ophthalmology (Rochester, Minn.)
影响因子：
--
作者：
P. T. Finger;P. T. Finger;Samuel Packer;Samuel Packer;Robert W. Paglione;Joseph F. Gatz;Tony K. Ho;Tony K. Ho;J. L. Bosworth;J. L. Bosworth
通讯作者：
J. L. Bosworth
经瞳孔热疗治疗脉络膜黑色素瘤：100 例连续病例的肿瘤控制和视力结果。
DOI：
--
发表时间：
1998
期刊：
Ophthalmology (Rochester, Minn.)
影响因子：
--
作者：
C. Shields;J. Shields;J. Cater;N. Lois;C. Edelstein;K. Gündüz;G. Mercado
通讯作者：
G. Mercado
铁磁热疗和碘 125 近距离放射治疗治疗兔模型脉络膜黑色素瘤。
DOI：
--
发表时间：
1989
期刊：
A M A Archives of Ophthalmology
影响因子：
--
作者：
W. Mieler;Glenn J. Jaffe;Richard A. Steeves
通讯作者：
Richard A. Steeves