Pontine infarction with pure motor hemiparesis or hemiplegia: a prospective study.
Pontine infarction with pure motor hemiparesis or hemiplegia: a prospective study.
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脑桥梗死伴单纯运动性偏瘫或偏瘫：一项前瞻性研究
DOI：
10.1186/1471-2377-9-25
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发表时间：
2009-06-15
期刊：
影响因子：
2.6
通讯作者：
Yang Z
中科院分区：
文献类型：
--
作者：
Ling L;Zhu L;Zeng J;Liao S;Zhang S;Yu J;Yang Z
本研究旨在前瞻性观察早期伴有单纯运动性偏瘫(PMH)或偏瘫的桥脑梗塞的临床和神经影像特征。连续入选118例首次发病6小时内的缺血性卒中患者，其中50例表现为PMH或偏瘫，急性CT扫描阴性，磁共振成像(MRI)证实相应的脑桥或大脑梗死。比较桥脑梗塞与脑梗塞的临床和神经影像特点。脑桥梗死合并PMH或偏瘫占首次脑梗塞患者的10.2%(12/118)，占合并PMH或偏瘫且急性CT扫描阴性的患者的24%(12/50)。与脑梗死组比较，桥脑梗死组糖尿病发生率(50.0%比5.3%，P=0.001)、起病时头晕发生率(58.3%比21.1%，P=0.036)和进展性眩晕发生率(33.3%比2.6%，P=0.011)明显增加。脑桥梗死可表现为PMH或偏瘫，伴有更多的非眩晕、进展性病程和糖尿病。MRI可以在卒中发病后早期确定脑桥基底区的梗塞部位。
The study aimed to prospectively observe the clinical and neuroimaging features of pontine infarction with pure motor hemiparesis (PMH) or hemiplegia at early stage. In 118 consecutive selected patients with the first-ever ischemic stroke within 6 hours after onset, fifty of them presented with PMH or hemiplegia and had negative acute computed tomography (CT) scans, then magnetic resonance imaging (MRI) confirmed the corresponding infarcts in pons or cerebrum. The clinical and neuroimaging features of the pontine infarctions were compared with those of cerebral infarctions. The pontine infarction with PMH or hemiplegia accounted for 10.2% (12/118) of all first-ever ischemic stroke patients and 24% (12/50) of the patients with both PMH or hemiplegia and acute negative CT scans. Compared to the patients with cerebral infarction, the patients with pontine infarction had more frequency of diabetes mellitus (50.0% vs 5.3%, P = 0.001), nonvertiginous dizziness at onset (58.3% vs 21.1%, P = 0.036) and a progressive course (33.3% vs 2.6%, P = 0.011). The pontine infarction may present as PMH or hemiplegia with more frequency of nonvertiginous dizziness, a progressive course and diabetes mellitus. MRI can confirm the infarct location in the basal pons at early stage after stroke onset.
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