How many clinic BP readings are needed to predict cardiovascular events as accurately as ambulatory BP monitoring?
How many clinic BP readings are needed to predict cardiovascular events as accurately as ambulatory BP monitoring?
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需要多少临床血压读数才能像动态血压监测一样准确地预测心血管事件？
DOI：
10.1038/jhh.2014.8
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kario K.
中科院分区：
文献类型：
--
作者：
Eguchi K;Hoshide S;Shimada K;Kario K.
我们测试了这样的假设：延长基线期内的多次门诊血压（BP）读数对于心血管疾病（CVD）的预测性与动态血压（ABP）一样。对457例高血压病患者进行了门诊和动态血压监测。每月测量一次门诊血压，并将前3、5和10次门诊血压读数的平均值作为多次门诊血压读数。对受试者进行随访，并将卒中、硬CVD和ALL CVD事件确定为结局。在多变量考克斯回归分析中，动态收缩压（SBP）最能预测三种结局，独立于基线和多个门诊SBP读数。10次门诊SBP读数的平均值预测卒中（风险比（HR）= 1.39，95%置信区间（CI）= 1.02-1.90，P= 0.04）和ALL CVD（HR= 1.41，95% CI= 1.13-1.74，P= 0.002），与基线门诊SBP无关。除了门诊SBP 3次读数与ALL CVD相关（P= 0.015）外，门诊SBP 3次和5次读数与任何CVD事件无关。除ABP值外，前10个门诊SBP值的平均值是卒中和ALL CVD事件的重要预测因子。重要的是在基线期后早期进行多次门诊血压读数，以用于未来CVD事件的风险分层。
We tested the hypothesis that multiple clinic blood pressure (BP) readings over an extended baseline period would be as predictive as ambulatory BP (ABP) for cardiovascular disease (CVD). Clinic and ABP monitoring were performed in 457 hypertensive patients at baseline. Clinic BP was measured monthly and the means of the first 3, 5 and 10 clinic BP readings were taken as the multiple clinic BP readings. The subjects were followed up, and stroke, HARD CVD, and ALL CVD events were determined as outcomes. In multivariate Cox regression analyses, ambulatory systolic BP (SBP) best predicted three outcomes independently of baseline and multiple clinic SBP readings. The mean of 10 clinic SBP readings predicted stroke (hazards ratio (HR)= 1.39, 95% confidence interval (CI)= 1.02–1.90, P= 0.04) and ALL CVD (HR= 1.41, 95% CI= 1.13–1.74, P= 0.002) independently of baseline clinic SBP. Clinic SBPs by three and five readings were not associated with any CVD events, except that clinic SBP by three readings was associated with ALL CVD (P= 0.015). Besides ABP values, the mean of the first 10 clinic SBP values was a significant predictor of stroke and ALL CVD events. It is important to take more than several clinic BP readings early after the baseline period for the risk stratification of future CVD events.
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影响因子：
3.2
作者：
Ohkubo, T;Imai, Y;Hisamichi, S
通讯作者：
Hisamichi, S
影响因子：
24
作者：
Ohkubo, T;Kikuya, M;Imai, Y
通讯作者：
Imai, Y
影响因子：
3.2
作者：
Eguchi, Kazuo;Pickering, Thomas G.;Kario, Kazuomi
通讯作者：
Kario, Kazuomi
为了更好地预测中风风险，应该在家测量多少次血压？
DOI：
--
发表时间：
2004
期刊：
Journal of Hypertension 22
影响因子：
--
作者：
Ohkubo T;et al.
通讯作者：
et al.
抗高血压和降脂治疗预防心脏病试验（ALLHAT）。
影响因子：
5.6
作者：
J. Flack;Samar A. Nasser
通讯作者：
Samar A. Nasser