Conjoint control of hippocampal place cell firing by two visual stimuli. Ii. A vector-field theory that predicts modifications of the representation of the environment.
Conjoint control of hippocampal place cell firing by two visual stimuli. Ii. A vector-field theory that predicts modifications of the representation of the environment.
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DOI：
10.1085/jgp.116.2.211
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发表时间：
2000-08
期刊：
影响因子：
--
通讯作者：
Muller RU
中科院分区：
文献类型：
--
作者：
Fenton AA;Csizmadia G;Muller RU
改变两个视觉刺激之间的角度间隔连接到一个记录圆柱体的墙壁上，导致位置细胞的发射场相对于彼此移动，好像地板的代表经历了拓扑失真。每个细胞的放电场中心的位移是一个向量，其长度等于线性位移，其角度指示场中心在环境中移动的方向。根据观察，相邻的领域以类似的方式移动，而广泛分离的领域往往相对于彼此移动，我们开发了一个经验矢量场模型，占改变卡分离的影响。然后，我们继续表明，相同的矢量场方程预测实验结果的其他方面。在一个例子中，我们证明了位置细胞发射场经历扭曲的形状后，卡分离被改变，虽然不同的部分相同的字段的刺激星座的影响，在相同的方式作为字段在不同的位置。我们的结论是，矢量场形式主义反映了当前情况下的环境的位置细胞表示的组织，并通过适当的修改可能是非常有用的，用于描述运动的各种刺激操纵引起的发射模式。
Changing the angular separation between two visual stimuli attached to the wall of a recording cylinder causes the firing fields of place cells to move relative to each other, as though the representation of the floor undergoes a topological distortion. The displacement of the firing field center of each cell is a vector whose length is equal to the linear displacement and whose angle indicates the direction that the field center moves in the environment. Based on the observation that neighboring fields move in similar ways, whereas widely separated fields tend to move relative to each other, we develop an empirical vector-field model that accounts for the stated effects of changing the card separation. We then go on to show that the same vector-field equation predicts additional aspects of the experimental results. In one example, we demonstrate that place cell firing fields undergo distortions of shape after the card separation is changed, as though different parts of the same field are affected by the stimulus constellation in the same fashion as fields at different locations. We conclude that the vector-field formalism reflects the organization of the place-cell representation of the environment for the current case, and through suitable modification may be very useful for describing motions of firing patterns induced by a wide variety of stimulus manipulations.
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DOI：
10.1085/jgp.116.2.191
发表时间：
2000-08
期刊：
The Journal of general physiology
影响因子：
--
作者：
通讯作者：
--
DOI：
10.1073/pnas.95.6.3182
发表时间：
1998-03-17
影响因子：
11.1
作者：
Fenton, AA;Muller, RU
通讯作者：
Muller, RU
DOI：
10.1073/pnas.94.16.8918
发表时间：
1997-08-05
影响因子：
11.1
作者：
Mehta, MR;Barnes, CA;McNaughton, BL
通讯作者：
McNaughton, BL
影响因子：
5.3
作者：
FOX, SE;RANCK, JB
通讯作者：
RANCK, JB
影响因子：
1.9
作者：
Hetherington, PA;Shapiro, ML
通讯作者：
Shapiro, ML