Systematic coarse-graining of spectrin-level red blood cell models.
Systematic coarse-graining of spectrin-level red blood cell models.
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DOI:
10.1016/j.cma.2010.02.001
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发表时间:
2010-06-01
影响因子:
7.2
通讯作者:
Karniadakis GE
中科院分区:
文献类型:
--
作者:
Fedosov DA;Caswell B;Karniadakis GE
We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which yield accurate mechanical response. Based on a semi-analytic theory the linear and nonlinear elastic properties of healthy and infected RBCs in malaria can be matched with those obtained in optical tweezers stretching experiments. The present analysis predicts correctly the membrane Young’s modulus in contrast to about 50% error in predictions by previous models. In addition, we develop a stress-free model which avoids a number of pitfalls of existing RBC models, such as non-smooth or poorly controlled equilibrium shape and dependence of the mechanical properties on the initial triangulation quality. Here we employ dissipative particle dynamics for the implementation but the proposed model is general and suitable for use in many existing continuum and particle-based numerical methods.
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影响因子:
3.4
作者:
Takeuchi, M;Miyamoto, H;Kusumi, A
通讯作者:
Kusumi, A
DOI:
10.1016/j.msec.2005.08.020
发表时间:
2006-09-01
期刊:
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
影响因子:
--
作者:
Dao, M.;Li, J.;Suresh, S.
通讯作者:
Suresh, S.
影响因子:
3.4
作者:
Li, J;Dao, M;Suresh, S
通讯作者:
Suresh, S
影响因子:
3.4
作者:
Evans, James;Gratzer, Walter;Sleep, John
通讯作者:
Sleep, John
影响因子:
3.4
作者:
Discher, DE;Boal, DH;Boey, SK
通讯作者:
Boey, SK