Study on clinical outcomes between non-transecting urethroplasty and lingual mucosal urethroplasty for iatrogenic bulbar urethral stricture treatment.
Study on clinical outcomes between non-transecting urethroplasty and lingual mucosal urethroplasty for iatrogenic bulbar urethral stricture treatment.
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DOI：
10.1186/s12610-023-00185-z
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发表时间：
2023-05-04
影响因子：
2.4
通讯作者：
Li, Chao
中科院分区：
文献类型：
--
作者：
Le, Wei;Wu, Denglong;Xu, Chengdang;Zhou, Weidong;Li, Chao
比较非横断尿道成形术与舌粘膜尿道成形术治疗医源性球部尿道狭窄的临床疗效。25例医源性球部尿道狭窄患者，其中12例行舌黏膜尿道成形术，13例行非横断尿道成形术。所有患者均在术后3个月进行随访和评估。评估包括尿道造影、最大尿流率（Qmax）、夜间勃起功能测试、国际勃起功能指数（IIEF-5）评估和焦虑相关量表（SAS）评估。在手术时间方面，非横断尿道成形术与舌粘膜尿道成形术之间有显著差异。然而，术中失血量无显著组间差异。两种技术均与Qmax相对于术前率的显著改善相关，但在术后3个月随访期间，两组在这方面无显著差异。夜间阴茎肿胀和硬度结果显示，非横断尿道成形术组术后尖端硬度无显著变化。此外，IIEF-5评分表明，在主观术后勃起功能方面没有显著的组间差异。根据术后随访期间的初步心理评估，非横断尿道成形术患者的焦虑评分明显改善，但舌粘膜尿道成形术患者的平均SAS评分无显著变化。两种手术方法均能达到治疗医源性球部尿道狭窄的临床目的。非横断尿道成形术具有手术时间短、技术相对简单、保留大多数患者原有勃起功能的特点，手术效果不亚于舌黏膜尿道成形术，是治疗球部尿道狭窄的一种有前景的技术。
This study aimed to compare the clinical outcomes of non-transecting urethroplasty and lingual mucosal urethroplasty in the treatment of iatrogenic bulbar urethral stricture. A total of 25 patients with iatrogenic bulbar urethral stricture were enrolled, 12 of whom underwent lingual mucosal urethroplasty, 13 patients who underwent non-transecting urethroplasty. All patients were followed-up and evaluated at 3 postoperative months. Evaluations included urethrography, maximum urine flow rate (Qmax), nocturnal erectile function testing, International Index of Erectile Function (IIEF-5) assessment, and Anxiety Related Scale (SAS) assessment. In terms of operation time, there was a significant difference between non-transecting urethroplasty and lingual mucosal urethroplasty. However, there was no significant intergroup difference in intraoperative blood loss. Both techniques were associated with significantly improved Qmax relative to preoperative rates, but there was no significant difference between the groups in this regard over 3 months of postoperative follow-up. Nocturnal penile tumescence and rigidity results showed that there was no significant change in tip hardness after surgery in the non-transecting urethroplasty group. Moreover, IIEF-5 scores indicated that there was no significant intergroup difference in terms of subjective postoperative erectile function. According to the preliminary psychological evaluations during postoperative follow-up, the anxiety scores of patients undergoing non-transecting urethroplasty significantly improved, but there was no significant change in the mean SAS score among patients who underwent lingual mucosal urethroplasty. Both surgical methods can achieve the clinical goal of treating iatrogenic bulbar urethral stricture. Non-transecting urethroplasty has the characteristics of short operation time, relative technical simplicity, and retention of the original erectile function of most patients, and the surgical outcomes of non-transecting urethroplasty are not inferior to those of lingual mucosal urethroplasty, and it is a promising technique for widespread use to treat bulbar urethral strictures.
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影响因子：
2.6
作者：
Hillary CJ;Osman NI;Chapple CR
通讯作者：
Chapple CR
影响因子：
4.5
作者：
Andrich, Daniela E.;Mundy, Anthony R.
通讯作者：
Mundy, Anthony R.
影响因子：
6.6
作者：
Barbagli, Guido;De Angelis, Michele;Lazzeri, Massimo
通讯作者：
Lazzeri, Massimo
影响因子：
23.4
作者：
Barbagli, Guido;Montorsi, Francesco;Lazzeri, Massimo
通讯作者：
Lazzeri, Massimo
影响因子：
1.6
作者：
Zhou, Shu-Kui;Zhang, Jiong;Lazzeri, Massimo
通讯作者：
Lazzeri, Massimo