Treatment credibility, expectancy, and preference: Prediction of treatment engagement and outcome in a randomized clinical trial of hatha yoga vs. health education as adjunct treatments for depression.

Treatment credibility, expectancy, and preference: Prediction of treatment engagement and outcome in a randomized clinical trial of hatha yoga vs. health education as adjunct treatments for depression.
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治疗可信度、期望和偏好:哈他瑜伽与健康教育作为抑郁症辅助治疗的随机临床试验中治疗参与度和结果的预测。

DOI:
10.1016/j.jad.2018.05.009
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发表时间:
2018
影响因子:
6.6
通讯作者:
Miller,IvanW
Miller,IvanW
中科院分区:
医学2区
文献类型:
--
作者:
Uebelacker,LisaA;Weinstock,LaurenM;Battle,CynthiaL;Abrantes,AnaM;Miller,IvanW

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背景哈他瑜伽可能有助于缓解抑郁症状。本分析的目的是确定治疗方案偏好、可信度或预期是否可以预测抑郁症干预措施(瑜伽或对照组)的参与度或抑郁症症状随时间的严重程度。方法这是对哈他瑜伽与健康教育对照组治疗抑郁症的随机对照试验 (RCT) 的二次分析。抑郁症参与者 (n=122) 在 10 周内参加了多达 20 节课程,然后在 3 个月和 6 个月后完成了额外的评估。我们在随机分组前评估了治疗偏好,并在参与者参加第一堂课后评估了治疗可信度和期望。治疗“一致性”表明治疗偏好与指定治疗相匹配。结果治疗可信度、预期和一致性与治疗参与度无关。治疗预期调节了治疗组与抑郁症之间的关联。随着时间的推移,抑郁症的严重程度因瑜伽组的预期水平而异,但健康教育组则没有。控制基线抑郁症后,瑜伽组中具有平均或较高改善期望的参与者在急性干预和随访期间表现出比那些期望改善较低的参与者更低的抑郁症状。可信度存在类似模式的趋势。一致性与治疗结果无关。局限性这是次要的事后分析,应被视为假设生成。结论结果表明,只有针对积极针对抑郁症(瑜伽)的干预措施(而不是对照干预措施),预期才会提高成功的可能性。
BackgroundHatha yoga may be helpful for alleviating depression symptoms. The purpose of this analysis is to determine whether treatment program preference, credibility, or expectancy predict engagement in depression interventions (yoga or a control class) or depression symptom severity over time.MethodsThis is a secondary analysis of a randomized controlled trial (RCT) of hatha yoga vs. a health education control group for treatment of depression. Depressed participants (n = 122) attended up to 20 classes over a period of 10 weeks, and then completed additional assessments after 3 and 6 months. We assessed treatment preference prior to randomization, and treatment credibility and expectancy after participants attended their first class. Treatment “concordance” indicated that treatment preference matched assigned treatment.ResultsTreatment credibility, expectancy, and concordance were not associated with treatment engagement. Treatment expectancy moderated the association between treatment group and depression. Depression severity over time differed by expectancy level for the yoga group but not for the health education group. Controlling for baseline depression, participants in the yoga group with an average or high expectancy for improvement showed lower depression symptoms across the acute intervention and follow-up period than those with a low expectancy for improvement. There was a trend for a similar pattern for credibility. Concordance was not associated with treatment outcome.LimitationsThis is a secondary, post-hoc analysis and should be considered hypothesis-generating.ConclusionsResults suggest that expectancy improves the likelihood of success only for a intervention thought to actively target depression (yoga) and not a control intervention.
参加瑜伽治疗抑郁症试验的持续抑郁者对哈他瑜伽的看法。
DOI: 10.1016/j.ctim.2017.06.008
发表时间: 2017
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Uebelacker,LisaA;Kraines,Morganne;Broughton,MonicaK;Tremont,Geoffrey;Gillette,LTom;Epstein-Lubow,Gary;Abrantes,AnaM;Battle,Cynthia;Miller,IvanW
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