Effects of Check Size on Visual Cortex Activation Studied by Functional Magnetic Resonance Imaging

Effects of Check Size on Visual Cortex Activation Studied by Functional Magnetic Resonance Imaging
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通过功能磁共振成像研究检查大小对视觉皮层激活的影响

DOI:
10.1159/000055667
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发表时间:
2001
影响因子:
2.1
通讯作者:
J. Haselgrove
J. Haselgrove
中科院分区:
医学3区
文献类型:
--
作者:
A. Miki;Grant T. Liu;Z. Goldsmith;Lan Zhou;J. Siegfried;J. Hulvershorn;J. Raz;J. Haselgrove

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我们研究了棋盘视觉刺激时视觉皮层的功能磁共振成像(fMRI),以研究视觉皮层的激活是否在三个标准尺寸的棋盘视觉刺激中有所不同。我们在1.5 T时对8名正常受试者进行了功能磁共振成像,每名受试者都接受了最佳的屈光矫正。每个受试者都接受了由四种条件组成的实验:以8赫兹闪烁的黑白棋盘,有三种尺寸(0.25度、0.5度和1.0度),以及黑屏。在每个受试者的数据经过运动校正和空间归一化到标准大脑后,使用SPM96进行随机效应模型的群体数据分析。在三种检查尺寸中,0.5度检查时视觉皮层的激活信号变化最大。当在功能磁共振成像实验中使用标准尺寸的检查来刺激视觉皮层时,我们的结果表明,在8赫兹闪烁的0.5度检查在视觉皮层中产生最强烈的激活。
We studied functional magnetic resonance imaging (fMRI) of visual cortex during checkerboard visual stimulation with three standard check sizes to examine whether activation in the visual cortex varied among these sizes. We acquired fMRI at 1.5 T in 8 normal subjects, each receiving the best refractive correction. Each subject underwent an experiment consisting of four conditions: black and white checkerboards with three check sizes (0.25-, 0.5-, and 1.0-degree) flickering at 8 Hz, and a black screen. SPM96 was used for a group data analysis with a random effects model after each of the subject’s data was motion-corrected and spatially normalized to a standard brain. The activation in the visual cortex showed the greatest signal changes with the 0.5-degree check among the three check sizes. When standard check sizes are used to stimulate visual cortex in fMRI experiments, our results suggest that 0.5-degree checks flickering at 8 Hz produce the most vigorous activation in visual cortex.
DOI: 10.1126/science.7754376
发表时间: 1995-05-12
期刊: SCIENCE
影响因子: 56.9
作者:
SERENO, MI;DALE, AM;TOOTELL, RBH
通讯作者: TOOTELL, RBH
DOI: 10.1073/pnas.89.13.5951
发表时间: 1992-07-01
影响因子: 11.1
作者:
OGAWA, S;TANK, DW;UGURBIL, K
通讯作者: UGURBIL, K