Evidence that genomic incompatibilities and other multilocus processes impact hybrid fitness in a rattlesnake hybrid zone

Evidence that genomic incompatibilities and other multilocus processes impact hybrid fitness in a rattlesnake hybrid zone
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基因组不相容性和其他多位点过程影响响尾蛇杂交区杂交适应性的证据

DOI:
10.1111/evo.14612
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发表时间:
2022
期刊:
影响因子:
3.3
通讯作者:
Parker, Joshua M.
Parker, Joshua M.
中科院分区:
环境科学与生态学2区
文献类型:
--
作者:
Nikolakis, Zachary L.;Schield, Drew R.;Westfall, Aundrea K.;Perry, Blair W.;Ivey, Kathleen N.;Orton, Richard W.;Hales, Nicole R.;Adams, Richard H.;Meik, Jesse M.;Parker, Joshua M.

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杂交区提供了宝贵的机会,了解基因组机制,促进物种形成的中间阶段所涉及的因素提供洞察力。在这里,我们调查的两个响尾蛇种(Crotalus viridisandCrotalus oreganus concolor),经历了历史的异地分歧和最近的范围扩大和二次接触之间的杂交区的基因渗入。我们使用贝叶斯基因组无性系模型来表征这些谱系之间的基因组模式的渐渗,并确定基因座可能受到选择的杂交种。我们发现了大量基因组区域的证据,这些基因组区域具有偏离杂交后代基因组背景的偏向性祖先(即,过量祖先基因座),其倾向于与具有较高重组率的基因组区域相关。我们还确定了一套多余的祖先基因座,显示高度相关的等位基因频率(包括同种和异种组合)在物理上不连锁的基因组区域的杂交。我们的研究结果提供了证据,多个多位点的进化过程影响混合健身在这个系统中。
Hybrid zones provide valuable opportunities to understand the genomic mechanisms that promote speciation by providing insight into factors involved in intermediate stages of speciation. Here, we investigate introgression in a hybrid zone between two rattlesnake species (Crotalus viridisandCrotalus oreganus concolor) that have undergone historical allopatric divergence and recent range expansion and secondary contact. We use Bayesian genomic cline models to characterize genomic patterns of introgression between these lineages and identify loci potentially subject to selection in hybrids. We find evidence for a large number of genomic regions with biased ancestry that deviate from the genomic background in hybrids (i.e., excess ancestry loci), which tend to be associated with genomic regions with higher recombination rates. We also identify suites of excess ancestry loci that show highly correlated allele frequencies (including conspecific and heterospecific combinations) across physically unlinked genomic regions in hybrids. Our findings provide evidence for multiple multilocus evolutionary processes impacting hybrid fitness in this system.
DOI: --
发表时间: 2000-05
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