Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish.
Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish.
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DOI:
10.1126/science.aba5216
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发表时间:
2020-05-15
期刊:
影响因子:
--
通讯作者:
Schumer M
中科院分区:
文献类型:
--
作者:
Powell DL;García-Olazábal M;Keegan M;Reilly P;Du K;Díaz-Loyo AP;Banerjee S;Blakkan D;Reich D;Andolfatto P;Rosenthal GG;Schartl M;Schumer M
The establishment of reproductive barriers between populations can fuel the evolution of new species. A genetic framework for this process posits that “incompatible” interactions between genes can evolve that result in reduced survival or reproduction in hybrids. However, progress has been slow in identifying individual genes that underlie hybrid incompatibilities. We used a combination of approaches to map the genes that drive the development of an incompatibility that causes melanoma in swordtail fish hybrids. One of the genes involved in this incompatibility also causes melanoma in hybrids between distantly related species. Moreover, this melanoma reduces survival in the wild, likely because of progressive degradation of the fin. This work identifies genes underlying a vertebrate hybrid incompatibility and provides a glimpse into the action of these genes in natural hybrid populations.
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影响因子:
4.9
作者:
Culumber, Z. W.;Fisher, H. S.;Rosenthal, G. G.
通讯作者:
Rosenthal, G. G.
影响因子:
10.7
作者:
G贸mez, A;Volff, JN;Wellbrock, C
通讯作者:
Wellbrock, C
影响因子:
3.3
作者:
Cui, Rongfeng;Schumer, Molly;Rosenthal, Gil G.
通讯作者:
Rosenthal, Gil G.
DOI:
10.1111/j.1469-185x.1936.tb00911.x
发表时间:
1936-07-01
影响因子:
--
作者:
Dobzhansky, T
通讯作者:
Dobzhansky, T
DOI:
10.1007/bf00374056
发表时间:
1934-01-01
期刊:
ZEITSCHR ZELLJORSCH U MIKROSK ANAT
影响因子:
--
作者:
DOBZHANSKY, TH.
通讯作者:
DOBZHANSKY, TH.